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Heat Shock 70kDa Protein 8 (HSPA8) antibody

Antigen

Heat Shock 70kDa Protein 8 (HSPA8)

Synonyms LAP1, HSC54, HSC70, HSC71, HSP71, HSP73, NIP71, HSPA10, MGC29929, MGC131511
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human, Hamster

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Blocking Antibody (Inhibition)
6 references available
Catalog no. ABIN361818
Quantity
Price 174.90 $   Plus shipping costs $45.00
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Additional Information

Alternative name Hsc70 (Hsp73)
Gene ID 3312
UniProt P11142
Immunogen Amino acides 650-670 of human hsp73
Description Synonyms: Hsc54, Hsc71, Hsc73, Hsp71, Hsp73, HspA10, HspA8, LAP1, NIP71
Characteristics Accession Number: NP_006588.1
Specificity Detects 73kDa protein corresponding to the molecular mass of hsc70 on SDS PAGE immunoblots. Does not cross-react with hsp70.

Application Details

Application Notes 1: 1500-2,000 (WB)
Purification Rabbit antiserum
Storage Store at 4° C. Shipping Temperature: Blue Ice or 4° C
Storage Shipping Temp Max Blue Ice or 4 °C
Research Area Heat Shock Proteins, Serum/Plasma Proteins
Restrictions For Research Use only

Publications

Bork, Sander, Valencia: "An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 16, pp. 7290-4, 1992 (PubMed).

DeLuca-Flaherty, McKay, Parham et al.: "Uncoating protein (hsc70) binds a conformationally labile domain of clathrin light chain LCa to stimulate ATP hydrolysis." in: Cell, Vol. 62, Issue 5, pp. 875-87, 1990 (PubMed).

Rothman: "Polypeptide chain binding proteins: catalysts of protein folding and related processes in cells." in: Cell, Vol. 59, Issue 4, pp. 591-601, 1990 (PubMed).

Boorstein, Ziegelhoffer, Craig: "Molecular evolution of the HSP70 multigene family." in: Journal of molecular evolution, Vol. 38, Issue 1, pp. 1-17, 1994 (PubMed).

Cluett, Wood, Banta et al.: "Tubulation of Golgi membranes in vivo and in vitro in the absence of brefeldin A." in: The Journal of cell biology, Vol. 120, Issue 1, pp. 15-24, 1993 (PubMed).

Brown, Hong-Brown, Doxsey et al.: "Molecular chaperones and the centrosome. A role for HSP 73 in centrosomal repair following heat shock treatment." in: The Journal of biological chemistry, Vol. 271, Issue 2, pp. 833-40, 1996 (PubMed).

Alternatives

Alternatives for antigen "Heat Shock 70kDa Protein 8 (HSPA8)", type "Antibodies"
Hosts Rabbit (73), Mouse (24), Goat (9), Rat (9)
Reactivities Human (80), Rat (Rattus) (55), Mouse (Murine) (50), Cow (Bovine) (29), Chicken (28), Pig (Porcine) (23), Hamster (15), Dog (Canine) (9), Rabbit (5), Sheep (Ovine) (5), Fruit Fly (Drosophila melanogaster) (4), Monkey (4), Fish (3), Guinea Pig (3), Spinach (Spinacia oleracea) (3), Xenopus laevis (3), Arabidopsis (2), Caenorhabditis elegans (C. elegans) (2), Pea (Pisum sativum) (2), Wheat (Triticum) (2), Yeast (2), Cat (Feline) (1), Mycobacteria (1), Plant (1), Squash (Cucurbita) (1), Wheat germ (1), Yeast (Pichia pastoris) (1)
Applications Western Blotting (WB) (95), ELISA (52), Immunohistochemistry (IHC) (42), Immunoprecipitation (IP) (34), Immunofluorescence (IF) (28), Immunocytochemistry (ICC) (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Flow Cytometry (FACS) (7), Immunohistochemistry (Frozen Sections) (IHC (fro)) (7), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Functional Studies (Func) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
Conjugates Biotin (8), FITC (5), PE (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes Internal Region (10), Isoform 1 (3), N-Term (3), AA 650-670 (2), C-Term (2), AA 534-615 (1), AA 556-568 (1), AA 618-637 (1)