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C-JUN antibody (pSer243)

JUN Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN361922
  • Target See all C-JUN (JUN) Antibodies
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    Binding Specificity
    • 42
    • 41
    • 30
    • 29
    • 22
    • 16
    • 16
    • 15
    • 11
    • 11
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer243
    Reactivity
    • 378
    • 205
    • 188
    • 32
    • 28
    • 21
    • 17
    • 17
    • 16
    • 12
    • 12
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 372
    • 14
    • 2
    Rabbit
    Clonality
    • 347
    • 41
    Polyclonal
    Conjugate
    • 188
    • 24
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 14
    • 14
    • 13
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This C-JUN antibody is un-conjugated
    Application
    • 268
    • 134
    • 121
    • 89
    • 57
    • 44
    • 43
    • 43
    • 41
    • 23
    • 11
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    The antibody detects endogenous level of c-Jun only when phosphorylated at serine 243.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against nonphosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Peptide sequence around phosphorylation site of pSer243 (P-L-S (p) -P-I) derived from Human c-Jun. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotype
    IgG
    Top Product
    Discover our top product JUN Primary Antibody
  • Application Notes
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Yamamura, Kawakami, Hirata, Ueno, Saini, Majid, Dahiya: "Oncogenic functions of secreted Frizzled-related protein 2 in human renal cancer." in: Molecular cancer therapeutics, Vol. 9, Issue 6, pp. 1680-7, (2010) (PubMed).

  • Target
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    Alternative Name
    c-Jun (JUN Products)
    Synonyms
    AP-1 antibody, AP1 antibody, c-Jun antibody, fj36h07 antibody, wu:fj36h07 antibody, zgc:65863 antibody, Junc antibody, c-jun antibody, CG2275 antibody, D-Jun antibody, D-jun antibody, D-jun/Jra antibody, DJUN antibody, DJun antibody, Djun antibody, Dmel\\CG2275 antibody, JRA antibody, JUN antibody, Jun antibody, V antibody, cJun antibody, d-JRA antibody, d-Jun antibody, d-jun antibody, dAP-1 antibody, dJRA antibody, dJUN antibody, dJra antibody, dJun antibody, djun antibody, dm-Jun antibody, jra antibody, jun antibody, l(2)46Ef antibody, l(2)IA109 antibody, l(2R)IA109 antibody, Jun proto-oncogene, AP-1 transcription factor subunit antibody, jun proto-oncogene S homeolog antibody, jun proto-oncogene antibody, Jun-related antigen antibody, jun proto-oncogene L homeolog antibody, JUN antibody, Jun antibody, jun.S antibody, jun antibody, Jra antibody, jun.L antibody
    Background
    Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
    Molecular Weight
    43 kDa
    NCBI Accession
    NP_002219
    UniProt
    P05412
    Pathways
    MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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