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STAT6 antibody (pThr645)

STAT6 Reactivity: Human IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN361971
  • Target See all STAT6 Antibodies
    STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
    Binding Specificity
    • 34
    • 16
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr645
    Reactivity
    • 133
    • 71
    • 60
    • 10
    • 10
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 113
    • 19
    • 4
    • 1
    Rabbit
    Clonality
    • 101
    • 35
    Polyclonal
    Conjugate
    • 78
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This STAT6 antibody is un-conjugated
    Application
    • 71
    • 44
    • 43
    • 27
    • 26
    • 26
    • 25
    • 19
    • 16
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Specificity
    The antibody detects endogenous level of STAT6 only when phosphorylated at threonine 645.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Peptide sequence around phosphorylation site of pThr645 (P-A-T (p) -I-K) derived from Human STAT6. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotype
    IgG
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  • Application Notes
    Immunohistochemistry: 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
    Alternative Name
    STAT6 (STAT6 Products)
    Synonyms
    D12S1644 antibody, IL-4-STAT antibody, STAT6B antibody, STAT6C antibody, signal transducer and activator of transcription 6 antibody, signal transducer and activator of transcription 6-like antibody, STAT6 antibody, Stat6 antibody, LOC100859543 antibody
    Background
    Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.
    Molecular Weight
    110 kDa
    NCBI Accession
    NP_003144
    UniProt
    P42226
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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