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beta Catenin antibody (pSer45)

CATNB Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN362090
  • Target See all beta Catenin (CATNB) Antibodies
    beta Catenin (CATNB) (Catenin, beta (CATNB))
    Binding Specificity
    • 43
    • 27
    • 21
    • 21
    • 20
    • 18
    • 17
    • 17
    • 17
    • 16
    • 16
    • 15
    • 9
    • 8
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer45
    Reactivity
    • 329
    • 246
    • 223
    • 27
    • 23
    • 22
    • 18
    • 16
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 272
    • 56
    • 4
    • 2
    • 1
    Rabbit
    Clonality
    • 267
    • 68
    Polyclonal
    Conjugate
    • 122
    • 22
    • 15
    • 15
    • 15
    • 15
    • 15
    • 15
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    This beta Catenin antibody is un-conjugated
    Application
    • 206
    • 158
    • 120
    • 118
    • 74
    • 60
    • 60
    • 49
    • 34
    • 31
    • 22
    • 8
    • 7
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    The antibody detects endogenous level of b-Catenin only when phosphorylated at threonine 41/serine 45.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Peptide sequence around phosphorylation site of pThr 41, pSer45 (A-T-T (p) -T-A-P-S (p) -L-S) derived from Human b-Catenin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotype
    IgG
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  • Application Notes
    Western blotting: 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    beta Catenin (CATNB) (Catenin, beta (CATNB))
    Alternative Name
    beta-Catenin (CATNB Products)
    Background
    Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.
    Molecular Weight
    92 kDa
    NCBI Accession
    NP_001091
    UniProt
    P35222
    Pathways
    Peptide Hormone Metabolism
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