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BCR antibody (pTyr177)

BCR Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN362226
  • Target See all BCR Antibodies
    BCR (Breakpoint Cluster Region (BCR))
    Binding Specificity
    • 31
    • 16
    • 14
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr177
    Reactivity
    • 117
    • 76
    • 33
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 108
    • 13
    • 4
    Rabbit
    Clonality
    • 112
    • 13
    Polyclonal
    Conjugate
    • 58
    • 10
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This BCR antibody is un-conjugated
    Application
    • 66
    • 39
    • 36
    • 30
    • 26
    • 26
    • 19
    • 15
    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    The antibody detects endogenous level of Bcr only when phosphorylated at tyrosine 177.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Peptide sequence around phosphorylation site of pTyr177 (P-F-Y (p) -V-N) derived from Human Bcr. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotype
    IgG
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    Discover our top product BCR Primary Antibody
  • Application Notes
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    BCR (Breakpoint Cluster Region (BCR))
    Alternative Name
    Bcr (BCR Products)
    Synonyms
    si:dkey-83d9.7 antibody, zK83D9.7 antibody, BCR antibody, ALL antibody, BCR1 antibody, CML antibody, D22S11 antibody, D22S662 antibody, PHL antibody, 5133400C09Rik antibody, AI561783 antibody, AI853148 antibody, mKIAA3017 antibody, breakpoint cluster region antibody, BCR, RhoGEF and GTPase activating protein antibody, bcr antibody, BCR antibody, Bcr antibody
    Background
    GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.
    Molecular Weight
    210 kDa
    NCBI Accession
    NP_004318
    UniProt
    P11274
    Pathways
    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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