Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) (AA 891-895) antibody

Details for Product No. ABIN362515
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Antigen
Synonyms
EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50, NF-kB, NF-KB1, NF-kappaB1, p50/p105, BICDR-1, bicdr1, ccdc64, ebp-1, kbf1, nf-kappa-b, nf-kappaB, nfkb-p105, nfkb- ... show more
EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50, NF-kB, NF-KB1, NF-kappaB1, p50/p105, BICDR-1, bicdr1, ccdc64, ebp-1, kbf1, nf-kappa-b, nf-kappaB, nfkb-p105, nfkb-p50 show less
Epitope
AA 891-895
(36), (35), (34), (33), (32), (24), (13), (12), (11), (10), (6), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(434), (172), (143), (63), (52), (27), (27), (1), (1), (1)
Host
Rabbit
(419), (40), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(15), (11), (11), (8), (8), (8), (8), (8), (8), (8), (8), (2), (2), (2)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(348), (166), (165), (112), (80), (69), (36), (29), (12), (7), (7), (5), (5), (4), (2), (2), (1), (1)
Pubmed 4 references available
Catalog no. ABIN362515
Quantity 50 µL
Price
165.00 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide sequence around AA 891-895 (A-S-S-P-V) derived from Human NFkB-p105. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype IgG
Specificity The antibody detects endogenous level of total NFkB-p105 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name NFkappaB-p105/p50
Background NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
Molecular Weight 120 kDa
NCBI Accession NP_001158
UniProt P19838
Application Notes Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Background publications Haskill, Beg, Tompkins et al.: "Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity." in: Cell, Vol. 65, Issue 7, pp. 1281-9, 1991 (PubMed).

Baeuerle, Henkel: "Function and activation of NF-kappa B in the immune system." in: Annual review of immunology, Vol. 12, pp. 141-79, 1994 (PubMed).

Baeuerle, Baltimore: "NF-kappa B: ten years after." in: Cell, Vol. 87, Issue 1, pp. 13-20, 1996 (PubMed).

Hou, Guan, Ricciardi: "Phosphorylation of serine 337 of NF-kappaB p50 is critical for DNA binding." in: The Journal of biological chemistry, Vol. 278, Issue 46, pp. 45994-8, 2003 (PubMed).

Hosts (419), (40), (2), (1)
Reactivities (434), (172), (143), (63), (52), (27), (27), (1), (1), (1)
Applications (348), (166), (165), (112), (80), (69), (36), (29), (12), (7), (7), (5), (5), (4), (2), (2), (1), (1)
Conjugates (15), (11), (11), (8), (8), (8), (8), (8), (8), (8), (8), (2), (2), (2)
Epitopes (36), (35), (34), (33), (32), (24), (13), (12), (11), (10), (6), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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