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tau antibody (AA 354-358)

Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated

Catalog No. ABIN362658

Datasheet as PDF

Target See all tau Antibodies

tau (tau Protein)
Binding Specificity
31

30

30

26

26

26

24

23

23

21

19

18

17

17

17

17

16

16

16

16

16

15

15

15

15

13

11

9

8

8

8

7

6

6

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2
AA 354-358
Reactivity
524

499

498

40

28

27

18

6

3

2

1

1
Human, Mouse, Rat
Host
629

35

2

1
Rabbit
Compatible Secondaries
Clonality
604

62

1
Polyclonal
Conjugate
207

40

34

33

33

33

32

32

32

30

24

24

24

24

24

13

6

4

4

4

4

4

1

1
This tau antibody is un-conjugated
Application
548

272

263

205

92

85

67

59

52

35

34

15

12

12

12

9

2

2

1

1
Immunofluorescence (IF)

Specificity

The antibody detects endogenous level of total Tau protein.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogen

Peptide sequence around AA 354-358 (I-G-S-L-D) derived from Human Tau. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype

IgG

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Reactivity: Human, Mouse, Rat WB, ELISA, IF (p), IF (cc), IHC (p), FACS, IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-tau Protein antibody
Reactivity: Human WB, ELISA, IF, ICC, DB Host: Mouse Monoclonal 1D5 unconjugated

anti-tau Protein antibody (HRP)
Reactivity: Human WB, ELISA, IF, ICC, DB Host: Mouse Monoclonal 1D5 HRP

Application Notes

Immunofluorescence: 1:100-1:200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target

tau (tau Protein)

Alternative Name

Tau (tau Products)

Synonyms

DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, tau antibody, PHF-tau antibody, microtubule associated protein tau antibody, MAPT antibody

Background

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Molecular Weight

78 kDa

NCBI Accession

NP_001116

UniProt

P10636