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Stathmin 1 antibody (STMN1) (AA 23-27)

Details for Product anti-STMN1 Antibody No. ABIN362873, Supplier: Log in to see
Antigen
Alternatives
anti-Human Stathmin 1 antibody for ELISA
Epitope
AA 23-27
32
31
28
26
23
19
18
17
15
11
10
7
5
5
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
339
216
195
14
13
12
6
5
5
3
Host
Rabbit
315
18
8
Clonality
Polyclonal
Conjugate
This Stathmin 1 antibody is un-conjugated
6
4
4
4
3
3
3
3
3
3
3
3
2
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
260
190
106
66
58
38
15
8
6
4
3
2
2
1
Supplier
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Immunogen Peptide sequence around AA 23-27 (I-L-S-P-R) derived from Human Stathmin 1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype IgG
Specificity The antibody detects endogenous level of total Stathmin 1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
Alternative Name Stathmin 1 (STMN1 Antibody Abstract)
Background Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear
Molecular Weight 19 kDa
NCBI Accession NP_001138
UniProt P16949
Pathways MAPK Signaling, Microtubule Dynamics
Application Notes Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Background publications Vadlamudi, Barnes, Rayala et al.: "p21-activated kinase 1 regulates microtubule dynamics by phosphorylating tubulin cofactor B." in: Molecular and cellular biology, Vol. 25, Issue 9, pp. 3726-36, 2005 (PubMed).

Biernat, Wu, Timm et al.: "Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity." in: Molecular biology of the cell, Vol. 13, Issue 11, pp. 4013-28, 2002 (PubMed).

Boehm, Yoshimoto, Crook et al.: "A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression." in: The EMBO journal, Vol. 21, Issue 13, pp. 3390-401, 2002 (PubMed).

Zilfou, Hoffman, Sank et al.: "The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation." in: Molecular and cellular biology, Vol. 21, Issue 12, pp. 3974-85, 2001 (PubMed).