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BIM antibody (AA 67-71)
BCL2L11
Reactivity: Human, Mouse, Rat
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-BIM Antibody
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Target
See all BIM (BCL2L11) Antibodies
BIM (BCL2L11)
(BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
Binding Specificity
All epitopes for BIM antibodies
AA 67-71
Reactivity
All reactivities for BIM antibodies
Human, Mouse, Rat
Host
All hosts for BIM antibodies
Rabbit
Clonality
All clonalities for BIM antibodies
Polyclonal
Conjugate
All conjugates for BIM antibodies
This BIM antibody is un-conjugated
Application
All applications for BIM antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Specificity
The antibody detects endogenous level of total BIM protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Peptide sequence around AA 67-71 (P-A-S-P-G) derived from Human BIM. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for BIM
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Target
BIM (BCL2L11)
(BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
Alternative Name
BIM (BCL2L11 Products )
Synonyms
bim antibody, BAM antibody, BIM antibody, BOD antibody, 1500006F24Rik antibody, Bim antibody, Bod antibody, BimL antibody, BIMEL antibody, BCL2-like 11 antibody, BCL2 like 11 antibody, BCL2-like 11 (apoptosis facilitator) antibody, bcl2l11 antibody, BCL2L11 antibody, Bcl2l11 antibody
Background
Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS.
Molecular Weight
23 kDa
NCBI Accession
NP_006529
UniProt
O43521
Pathways
PI3K-Akt Signaling , Neurotrophin Signaling Pathway , Tube Formation , Positive Regulation of Endopeptidase Activity
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