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SMAD2 antibody (AA 463-467)

SMAD2 Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN363043
  • Target See all SMAD2 Antibodies
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    Binding Specificity
    • 47
    • 37
    • 30
    • 26
    • 21
    • 16
    • 9
    • 9
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 463-467
    Reactivity
    • 236
    • 150
    • 117
    • 12
    • 12
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 239
    • 10
    Rabbit
    Clonality
    • 213
    • 36
    Polyclonal
    Conjugate
    • 127
    • 18
    • 12
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    This SMAD2 antibody is un-conjugated
    Application
    • 211
    • 101
    • 64
    • 53
    • 52
    • 44
    • 41
    • 39
    • 18
    • 14
    • 10
    • 10
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Specificity
    The antibody detects endogenous level of total Smad2 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    Immunogen
    Peptide sequence around AA 463-467 (C-S-S-M-S) derived from Human Smad2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotype
    IgG
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  • Application Notes
    Western blotting: 1:500-1:1000
    Immunofluorescence: 1:100-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    Alternative Name
    Smad2 (SMAD2 Products)
    Synonyms
    JV18 antibody, JV18-1 antibody, MADH2 antibody, MADR2 antibody, hMAD-2 antibody, hSMAD2 antibody, jv18 antibody, Xmad2 antibody, madh2 antibody, madr2 antibody, XSmad2 antibody, hmad-2 antibody, hsmad2 antibody, jv18-1 antibody, smad-2 antibody, fj43c06 antibody, wu:fj43c06 antibody, 7120426M23Rik antibody, Madh2 antibody, Madr2 antibody, Smad-2 antibody, mMad2 antibody, MAD homolog 2 antibody, Mothers against DPP homolog 2 antibody, SMAD 2 antibody, Smad2 antibody, SMAD family member 2 antibody, SMAD family member 2-Z antibody, SMAD family member 2 S homeolog antibody, SMAD2 antibody, SMAD2Z antibody, smad2 antibody, smad2.S antibody, Smad2 antibody
    Background
    Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.
    Molecular Weight
    60 kDa
    NCBI Accession
    NP_001003
    UniProt
    Q15796
    Pathways
    Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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