IL1R1 antibody (Extracellular Domain)
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- Target See all IL1R1 Antibodies
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
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Binding Specificity
- Extracellular Domain
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL1R1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA)
- Brand
- IHC-plus™
- Specificity
- These antibodies react with cell surface and soluble human IL-1 receptor, Specific epitopes are unknown, but they do partially inhibit (30-50 % ) binding of one another to IL-1 receptor. They do not block binding of IL-1 to receptor, and they do not cross-react with receptors for human IL-2 or IL-4.
- Purification
- Protein G purified
- Immunogen
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The extracellular domain of the type I human IL-1 receptor.
Type of Immunogen: Protein - Clone
- 40101
- Isotype
- IgG2b
- Top Product
- Discover our top product IL1R1 Primary Antibody
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- Application Notes
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Approved: ELISA, IHC, IHC-P (10 μg/mL), RIA
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. ELISA: Can be used as capture reagents or second antibody at a concentration of 5 μg/mL. RIA: Concentrations of 20-30 ng/mL of these antibodies will bind radiolabeled IL-1 receptor in a radioimmunoassay format. Immunocytochemistry: IL-1 receptor can be detected on cultured cells using antibody concentrations of 10-100 μg/mL.
Not recommended for: WB - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4. Sourced in Ascites.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Short term: -20°C
Long term: -70°C
Avoid freeze-thaw cycles.
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- Target
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Alternative Name
- IL1RA / IL1R1 (IL1R1 Products)
- Synonyms
- CD121A antibody, D2S1473 antibody, IL-1R-alpha antibody, IL1R antibody, IL1RA antibody, P80 antibody, CD121a antibody, CD121b antibody, IL-iR antibody, Il1r-1 antibody, DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, interleukin 1 receptor type 1 antibody, interleukin 1 receptor, type I antibody, interleukin 1 receptor-like 1 antibody, IL1R1 antibody, Il1r1 antibody, Il1rl1 antibody
- Background
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Name/Gene ID: IL1R1
Family: Interleukin
Synonyms: IL1R1, Antigen CD121a, D2S1473, IL-1R-1, IL-1R-alpha, IL-1RT-1, IL-1RT1, IL1R, IL1RA, IL1RT1, Interleukin receptor 1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, CD121A, CD121a antigen, Interleukin 1 receptor, type I, Interleukin-1 receptor type I, Interleukin-1 type i receptor, p80 - Gene ID
- 3554
- UniProt
- P14778
- Pathways
- NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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