FANCG antibody (AA 609-622)

Catalog No. ABIN364391

Product Details anti-FANCG Antibody

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Binding Specificity: AA 609-622

Reactivity: Human, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This FANCG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human FANCG.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Marmoset, Dog (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide LEEFRTSLPKSCDL from the C-terminus of human FANCG (NP_004620.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Marmoset, Dog (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3 μg/mL), Peptide-ELISA (1:32000), WB (0.5 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Alternative Name: FANCG (FANCG Products)

Background: Name/Gene ID: FANCG

Synonyms: FANCG, DNA repair protein XRCC9, Fanconi anemia group G protein, FAG, Protein FACG, XRCC9

Gene ID: 2189

NCBI Accession: NP_004620

UniProt: O15287

Pathways: DNA Damage Repair