Serotonin Receptor 5A (HTR5A) antibody

Antigen: Serotonin Receptor 5A (HTR5A)

Synonyms: 5-HT5A, MGC138226, Htr5, MR22, 5HT5A, HTR5A, si:dkey-265a7.5

Clonality: Monoclonal (2D3)

Host: Mouse

Reactivity: Human, Rat (Rattus)

Application: ELISA, Immunohistochemistry (IHC)

Catalog no.: ABIN368638

Additional Information

Alternative name: HTR5A

Gene ID: 3361

Immunogen: Partial peptide of Human HTR5A (1st extracellular domain)

Format: Affinity-purified

Isotype: IgG1 kappa  (Matching secondary antibodies)

Clone: 2D3

Description: Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. Subcellular location: Cell membrane, Multi-pass membrane protein. Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Application Details

Application Notes: Recommended dilutions: ELISA - 1ug/ml, IHC - 5.0ug/ml

Concentration: 0.25 mg/ml

Purification: ProteinG Affinity Purified

Buffer: PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]

Storage: Store below -20°C

Research Area: Signaling

Restrictions: For Research Use only

Images

Rat brain tissue

Rat brain tissue

Publications

Publications: Rees, den Daas, Foord et al.: "Cloning and characterisation of the human 5-HT5A serotonin receptor." in: FEBS letters, Vol. 355, Issue 3, pp. 242-6, 1995 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Sjoeblom, Jones, Wood et al.: "The consensus coding sequences of human breast and colorectal cancers." in: Science (New York, N.Y.), Vol. 314, Issue 5797, pp. 268-74, 2006 (PubMed).