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CD90 antibody (THY1)

Details for Product anti-THY1 Antibody No. ABIN371032, Supplier: Log in to see
Antigen
  • CD7
  • CD90
  • T25
  • Thy-1
  • Thy-1.2
  • Thy1.1
  • Thy1.2
Reactivity
Mouse (Murine)
273
248
123
29
28
26
21
21
10
5
4
4
3
2
2
1
Host
Rat
293
190
97
15
Clonality (Clone)
Monoclonal ()
Conjugate
This CD90 antibody is un-conjugated
80
67
54
35
7
5
5
5
5
5
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
420
146
105
97
73
59
36
30
30
27
12
10
9
9
5
4
3
2
2
1
Supplier
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Clone 30-H12
Isotype IgG2b
Specificity This antibody recognises CD90.2/Thy-1.2 alloantigen (Mr. 18 kDa). It does not cross react with Mouse and Rat strains bearing the Thy-1.1 alloantigen (e.g., AKR/J,PL). (Ref.2-5).
Characteristics Synonyms: Thy1.2, Thy-1.2, CD90, Thy-1, Thy-1 membrane glycoprotein
Endotoxin Level Low Endotoxin
Alternative Name CD90 (THY1 Antibody Abstract)
Background CD90/Thy-1 is a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily, consisting of a single V-set domain. (Ref.1-3) The Thy-1.2 alloantigen is expressed on all thymocytes, peripheral T lymphocytes, and some intraepithelial T cells of most mouse strains. It is also expressed in the brain and at varying levels on other non-lymphoid tissues.Synonyms: CD90, Thy-1, Thy-1 membrane glycoprotein, Thy-1.2, Thy1.2
Gene ID 21838
UniProt P01831
Research Area CD Antigens, Surface Receptors of Immune Cells, Experimental Models
Application Notes Flow Cytometry. (Ref.4,5)Immunohistochemistry on Frozen Sections. (Ref.6)In vivo and in vitro Depletion of T Cells. (Ref.7,8)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS without preservatives.
Preservative Without preservative
Storage -20 °C
Storage Comment Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Homans, Ferguson, Dwek, Rademacher, Anand, Williams: "Complete structure of the glycosyl phosphatidylinositol membrane anchor of rat brain Thy-1 glycoprotein." in: Nature, Vol. 333, Issue 6170, pp. 269-72, 1988

Williams, Gagnon: "Neuronal cell Thy-1 glycoprotein: homology with immunoglobulin." in: Science (New York, N.Y.), Vol. 216, Issue 4547, pp. 696-703, 1982

Ledbetter, Rouse, Micklem, Herzenberg: "T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views." in: The Journal of experimental medicine, Vol. 152, Issue 2, pp. 280-95, 1980

Ledbetter, Herzenberg: "Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens." in: Immunological reviews, Vol. 47, pp. 63-90, 1980