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CTLA4 antibody (PE)

CTLA4 Reactivity: Mouse FACS Host: Hamster Monoclonal 1B8 PE
Catalog No. ABIN371059
  • Target See all CTLA4 Antibodies
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Reactivity
    • 91
    • 60
    • 35
    • 5
    • 4
    Mouse
    Host
    • 62
    • 47
    • 13
    • 10
    • 1
    • 1
    Hamster
    Clonality
    • 77
    • 54
    • 2
    Monoclonal
    Conjugate
    • 64
    • 15
    • 13
    • 12
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTLA4 antibody is conjugated to PE
    Application
    • 80
    • 65
    • 52
    • 33
    • 17
    • 17
    • 14
    • 13
    • 10
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    Flow Cytometry (FACS)
    Specificity
    This Monoclonal antibody is specific to CD152/CTLA-4.
    Characteristics
    Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
    Clone
    1B8
    Isotype
    IgG
    Top Product
    Discover our top product CTLA4 Primary Antibody
  • Application Notes
    Flow Cytometry: < / = 0.3 μg/10^6 cells. (Ref.1,2)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Alternative Name
    CD152 / CTLA4 (CTLA4 Products)
    Synonyms
    CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody
    Background
    The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. (Ref.1-4) However CD152 is thought to be a negative regulator of T cell activation (Ref.1-3) and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer (Ref.1), and is relatively conserved among Humans, Mice and Chickens. (Ref.2)Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
    Gene ID
    100505288
    UniProt
    P09793
    Pathways
    Cancer Immune Checkpoints
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