Klra6 antibody (FITC)

Catalog No. ABIN371093

Product Details anti-Klra6 Antibody (FITC)

Target: Klra6 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 6 (Klra6))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Klra6 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: This antibody HBF-719 reacts with the B6 allele of Ly49F. It stains ~ 11 % of NK1.1+CD3- splenocytes, and 3.5 % (2.5 month old) to 10.0 % (11 month old) of CD8+ spleen cells from C57BL/6 mice. (Ref.1)

Characteristics: Synonyms: Ly-49f, Ly49-f, Ly49F, Killer cell lectin-like receptor 6, T-cell surface glycoprotein Ly-49F,Lymphocyte antigen 49f

Immunogen: CHO cells transfected with the B6 allele of Ly49F. (Ref. 1)

Clone: HBF-719

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1,3)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Klra6

Target: Klra6 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 6 (Klra6))

Alternative Name: KLRA6 (Klra6 Products)

Background: Ly49F is a member of the lectin like homodimeric Ly49 family of cell surface receptors. (Ref.1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells.Synonyms: Killer cell lectin-like receptor 6, Ly-49f, Ly49-f, Ly49F, Lymphocyte antigen 49f, T-cell surface glycoprotein Ly-49F

Gene ID: 16637

UniProt: Q60653