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Details for Product No. ABIN371557

Complement Decay-Accelerating Factor (CD55) antibody (FITC)

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Antigen
Synonyms CR, TC, DAF, CROM
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
Application
»Alternatives Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN371557
Quantity 100 tests
Price
275.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Clone 143-30
Isotype IgG1
Characteristics Synonyms: Complement decay-accelerating factor
Alternative Name CD55 / DAF
Background CD55, also known as decay accelerating factor (DAF), is a 64-73 kDa GPI-anchored singlechain glycoprotein that is expressed on all cells in contact with serum, including allhematopoietic cells and the vascular endothelium. A soluble form of CD55 is present inplasma and body fluids. CD55 is a member of the regulator of complement activity (RCA)family of proteins and is thought to play a role in the protection of cells from damage byautologous complement by preventing the amplification steps of the complement cascade. CD55 expression increases upon T cell activation and antibodies to CD55 are mitogenic inthe presence of phorbol esters. (Ref. 1-5)
UniProt P08174
Application Notes Flow Cytometry: 10 µL/10e6 cells. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.09% Sodium Azide as preservative.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Holmes, Simpson, Wainwright et al.: "Preferential expression of the complement regulatory protein decay accelerating factor at the fetomaternal interface during human pregnancy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 8, pp. 3099-105, 1990 (PubMed).

Liszewski, Farries, Lublin et al.: "Control of the complement system." in: Advances in immunology, Vol. 61, pp. 201-83, 1996 (PubMed).

Alternatives for antigen "Complement Decay-Accelerating Factor (CD55)", type "Antibodies"
Hosts (138), (44), (8), (4), (2), (1), (1)
Reactivities (179), (14), (14), (4), (3), (1)
Applications (135), (77), (30), (30), (24), (22), (14), (11), (11), (10), (3), (3), (1), (1)
Conjugates (26), (21), (19), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (4), (3), (3), (2), (1), (1), (1), (1), (1)
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