HHV8 antibody (AA 122-329)

Catalog No. ABIN371871

Product Details anti-HHV8 Antibody

Target: HHV8 (Herpes Virus Type 8 (HHV8))

Binding Specificity: AA 122-329

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HHV8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: The antibody recognizes the ORF73 protein of Human herpesvirus 8 (HHV-8).

Characteristics: Synonyms: ORF73, HHV-8

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human ORF73/HHV8 (122-329 aa) purified from E. coli

Clone: AT4C11

Isotype: IgG2a

Application Details

Application Notes: ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on Paraffin embedded sections (1: 50).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for HHV8

Target: HHV8 (Herpes Virus Type 8 (HHV8))

Alternative Name: Herpes Virus Type 8 / HHV8 (HHV8 Products)

Target Type: Virus

Background: ORF73 protein of human herpesvirus 8 (HHV-8) is a Kaposi's sarcoma-associated herpesvirus (KSHV) latent protein which has been suspected of playing a crucial role in modulating viral and cellular gene expression. ORF73 is associated with cellular chromatin and stays on the chromosomes during cell division. It maintains the viral genomes during cell division by tethering the viral episomes to the chromosomes. It binds directly to replication origin recognition complexes (ORCs) that are primarily associated with the terminal repeat (TR) region of the HHV-8 genome.Synonyms: HHV-8, Human herpesvirus 8 type P ORF73 protein, Kaposi's sarcoma-associated herpesvirus encoded protein ORF73, LANA-1, LNA, LNA1, ORF-73

Gene ID: 4961527

UniProt: Q9QR71