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Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibody
| Antigen | Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) |
| Synonyms |
AAT6, ACTSA, Actvs, a-SMA, SMalphaA, 0610041G09Rik, wu:fb63d03, MGC78870, ACTA2, actc1, actsa, MGC89192, MGC127800, ACT-4, DKFZp469E0314, Acta2, asma, acta, cftd, mpfd, nem1, nem2, nem3, acta2, cftd1, ...
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| Clonality | Monoclonal (1A4) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Cow (Bovine) |
| Application |
Alternatives Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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| Catalog no. | ABIN371892 |
| Quantity | 0.1 ml (Variants) |
| Price | 165.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | Synonyms: Alpha-actin-2, ACTVS, GIG46, Cell growth-inhibiting gene 46 protein |
| Alternative name | Aortic smooth muscle Actin / ACTA2 |
| Gene ID | 59 |
| Swiss-Prot | P62736 |
| Immunogen | A synthetic peptide from N-terminus of Human alpha smooth muscle isoform of Actin. Epitope: N-terminus |
| Cross-Reactivity | Cow (Bovine), Chicken, Human, Mouse (Murine), Rabbit, Rat (Rattus) |
| Isotype | IgG1 (Matching secondary antibodies) |
| Clone | 1A4 |
| Description | Actin is a major component of the cytoskeleton and is present in every cell type. Actin canbe resolved on the basis of its isoelectric points into three distinctive components: alpha,beta and gamma in order of increasing isoelectric point. Smooth Muscle Actin Ab does notstain cardiac or skeletal muscle. However, it will stain myofibroblasts and myoepithelialcells. This antibody could be used together with Muscle Specific Actin to distinguishleiomyosarcoma from rhabdomyosarcoma. |
| Specificity | This antibody stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also stained. It reacts with tumorsarising from smooth muscles and myoepithelial cells. Actin from fibroblasts (beta- andgamma-cytoplasmic), striated muscle (alpha-sarcomeric), and myocardium(alpha-myocardial) are not labeled. |
| Synonyms | AAT6, ACTSA, Actvs, a-SMA, SMalphaA, 0610041G09Rik, wu:fb63d03, MGC78870, ACTA2, actc1, actsa, MGC89192, MGC127800, ACT-4, DKFZp469E0314, Acta2, asma, acta, cftd, mpfd, nem1, nem2, nem3, acta2, cftd1, cftdm, MGC52636, MGC79039 |
Application Details
| Application Notes | Immunofluorescence. Immunohistochemistry with Formalin-Fixed, Paraffin-Embedded tissues: 1/200. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer,pH 6.0 for 10 min followed by cooling at RT for 20 min. Slides must be washed in betweensteps. Rinse slides with PBS/0.05% Tween. Incubation Time: 30 minutes at RT. Positive Control: Smooth Muscle or leimyosarcoma. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Purification | Purified |
| Buffer | 10mM PBS, pH 7.4 with 1% BSA as stabilizer and 0.09% Sodium Azide aspreservative. |
| Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch. |
| Research Area | Extracellular Matrix, Cell/Tissue Markers |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Actin, alpha 2, Smooth Muscle, Aorta (ACTA2)", type "Antibodies"
| Hosts | Mouse (33), Rabbit (11), Goat (4) |
| Reactivities | Human (35), Rat (Rattus) (17), Chicken (16), Mouse (Murine) (16), Cow (Bovine) (14), Rabbit (13), Baboon (3), Dog (Canine) (2), Monkey (2), Vertebrates (2) |
| Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (39), Western Blotting (WB) (18), Immunofluorescence (IF) (13), Immunohistochemistry (Frozen Sections) (IHC (fro)) (10), Enzyme Immunoassay (EIA) (7), Immunohistochemistry (IHC) (6), ELISA (5), ELISA (Detection) (1), Flow Cytometry (FACS) (1), Immunoprecipitation (IP) (1) |
| Epitopes | N-Term (5), Ab-1 (2) |
