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Antibody
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anti-Caveolin 1 Caveolae Protein 22kDa CAV1 C-Term
Caveolin 1, Caveolae Protein, 22kDa (CAV1) (C-Term) antibody
| Antigen |
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| Synonyms |
CAV, CGL3, BSCL3, VIP21, MSTP085, Cav, Cav-1, MGC187299, CAV1, fc07c04, wu:fc07c04, cav1a, cav1b, caveolin 1, cav, vip21, mstp085, MGC107940, Caveolin-1, cav1 |
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Epitope
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| Clonality |
Monoclonal (SP43) |
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Host
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Reactivity
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Application
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Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB) (53), Immunofluorescence (IF) (22), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (20), Flow Cytometry (FACS) (13), Enzyme Immunoassay (EIA) (12), ELISA (11), Immunohistochemistry (IHC) (6), Immunoprecipitation (IP) (6), Dot Blot (Dot) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (EM) (1)
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| Catalog no. |
ABIN371913 |
| Quantity |
1.0 ml (Variants) |
| Price |
580.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: CAV1
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Alternative name
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Caveolin-1 (C-term)
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Gene ID
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857
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Swiss-Prot
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Q03135
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Immunogen
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Synthetic peptide corresponding to C-terminus of Human Caveolin-1 protein. Remarks: Epitope: C-terminus.
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Clone
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SP43
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Description
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Caveolae (also known as plasmalemmal vesicles) are 50-100 nm flask-shaped membranesthat represent a subcompartment of the plasma membrane. On the basis of morphologicalstudies, caveolae have been implicated to function in the transcytosis of variousmacromolecules (including LDL( across capillary endothelial cells, uptake of smallmolecules via potocytosis and the compartmentalization of certain signaling moleculesincluding G protein-coupled receptors. Three proteins, caveolin-1, caveolin-2 andcaveolin-3 have been identified as principle components of caveolae.
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Specificity
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This antibody recognizes Caveolin-1. Cellular Localization: Cytoplasm and Membrane. Species Reactivity: Tested: Human. Add. Information: Molecular Weight: 22kDa
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Application Notes
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Immunohistochemistry with Formalin-Fixed, Paraffin-Embedded tissues: 1/50Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer,pH 6.0 for 10 min followed by cooling at RT for 20 min. Slides must be washed in betweensteps. Rinse slides with PBS/0.05% Tween. Incubation Time: 30 minutes at RT. Positive Control: Lung carcinoma. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Buffer
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10mM PBS, pH 7.4 with BSA as stabilizer and 0.09% Sodium Azide aspreservative.
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Storage
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Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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Restrictions
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For Research Use only
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Alternatives for antigen "Caveolin 1, Caveolae Protein, 22kDa (CAV1)", type "Antibodies"
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Hosts
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Rabbit (68), Goat (8), Mouse (6), Sheep (2)
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Reactivities
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Human (72), Rat (Rattus) (52), Mouse (Murine) (50), Dog (Canine) (6), Pig (Porcine) (5), Hamster (1)
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Applications
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Western Blotting (WB) (53), Immunofluorescence (IF) (22), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (20), Flow Cytometry (FACS) (13), Enzyme Immunoassay (EIA) (12), ELISA (11), Immunohistochemistry (IHC) (6), Immunoprecipitation (IP) (6), Dot Blot (Dot) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (EM) (1)
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Conjugates
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Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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pTyr14 (10), N-Term (8), 1t cytoplasmic domain (4), C-Term (4), internal (2), Y14 (1), non pTyr14 (1), pY14 (1)
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