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Caveolin 1, Caveolae Protein, 22kDa (CAV1) (C-Term) antibody

Antigen

Caveolin 1, Caveolae Protein, 22kDa (CAV1)

Synonyms CAV, CGL3, BSCL3, VIP21, MSTP085, Cav, Cav-1, MGC187299, CAV1, fc07c04, wu:fc07c04, cav1a, cav1b, caveolin 1, cav, vip21, mstp085, MGC107940, Caveolin-1, cav1
Epitope
Alternatives

C-Term

Clonality Monoclonal (SP43)
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Catalog no. ABIN371914
Quantity 0.1 ml  (Variants)
Price 215.00 $   Plus shipping costs $35.00
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Additional Information

Characteristics Synonyms: CAV1
Alternative name Caveolin-1
Gene ID 857
Swiss-Prot Q03135
Immunogen Synthetic peptide corresponding to C-terminus of Human Caveolin-1 protein. Remarks: Epitope: C-terminus.
Cross-Reactivity Human
Clone SP43
Description Caveolae (also known as plasmalemmal vesicles) are 50-100 nm flask-shaped membranesthat represent a subcompartment of the plasma membrane. On the basis of morphologicalstudies, caveolae have been implicated to function in the transcytosis of variousmacromolecules (including LDL( across capillary endothelial cells, uptake of smallmolecules via potocytosis and the compartmentalization of certain signaling moleculesincluding G protein-coupled receptors. Three proteins, caveolin-1, caveolin-2 andcaveolin-3 have been identified as principle components of caveolae.
Specificity This antibody recognizes Caveolin-1. Cellular Localization: Cytoplasm and Membrane. Species Reactivity: Tested: Human. Add. Information: Molecular Weight: 22kDa

Application Details

Application Notes Immunohistochemistry with Formalin-Fixed, Paraffin-Embedded tissues: 1/50Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer,pH 6.0 for 10 min followed by cooling at RT for 20 min. Slides must be washed in betweensteps. Rinse slides with PBS/0.05% Tween. Incubation Time: 30 minutes at RT. Positive Control: Lung carcinoma. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Purification Purified
Buffer 10mM PBS, pH 7.4 with BSA as stabilizer and 0.09% Sodium Azide aspreservative.
Storage Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Caveolin 1, Caveolae Protein, 22kDa (CAV1)", type "Antibodies"
Hosts Rabbit (78), Goat (8), Mouse (7), Sheep (2)
Reactivities Human (80), Rat (Rattus) (56), Mouse (Murine) (50), Dog (Canine) (8), Pig (Porcine) (5), Cow (Bovine) (2), Horse (Equine) (2), Chicken (1), Hamster (1), Rabbit (1)
Applications Western Blotting (WB) (60), Immunofluorescence (IF) (31), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (21), Flow Cytometry (FACS) (18), Enzyme Immunoassay (EIA) (13), ELISA (11), Immunohistochemistry (IHC) (7), Immunoprecipitation (IP) (7), Dot Blot (Dot) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes pTyr14 (10), N-Term (8), 1t cytoplasmic domain (4), C-Term (4), Y14 (1), internal (1), pY14 (1)