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Antibodies
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anti-Peripherin (PRPH) (AA 265-471) antibody
Peripherin (PRPH) (AA 265-471) antibody
| Antigen |
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| Synonyms |
NEF4, PRPH1, Prph1, Perf, nef4, prph1, MGC69454 |
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Epitope
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AA 265-471
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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| Catalog no. |
ABIN372196 |
| Quantity |
50 µg (0.2 mg/ml) |
| Price |
390.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: PRPH, NEF4, PRPH1
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Alternative name
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Peripherin
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Swiss-Prot
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P41219
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Immunogen
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Recombinant protein corresponding to the Amino acids 265-471 of human PRPH.
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Cross-Reactivity
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Human
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Peripherin is a Class III intermediate filament subunit found in both the peripheral andcentral nervous systems, though it is concentrated, as its name suggests, in the neurons ofperipheral ganglia and their processes. Antibodies to peripherin can be used in identifying,classifying, and studying neurons in the nervous system. Peripherin is also a gooddiagnostic marker for ballooned axons seen in Lou Gehrigs disease and some neuronallyderived tumors. Peripherin is also a major component of the cytoskeleton of PC12 cells, awidely used model system for studies of neuronal differentiation. Autoantibodies toperipherin are frequently seen in the sera of patients with diabetes. Peripherin is notrelated to peripherin RDS, a photoreceptor protein associated with retinal degenerationand blindness.
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Specificity
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This antibody is specific to Peripherin (PRPH). Species: Human. Others not tested.
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Application Notes
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Immunohistochemistry on Paraffin Sections: 2.5 µg/ml. Western Blot: 1-2 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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0.2 mg/ml
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Purification
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Ig Fraction
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Buffer
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PBS, pH 7.4 containing 0.05% Sodium Azide as preservative and 0.2% BSAas stabilizer.
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Restrictions
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For Research Use only
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Alternatives for antigen "Peripherin (PRPH)", type "Antibodies"
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Hosts
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Rabbit (13), Mouse (10), Chicken (6)
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Reactivities
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Human (15), Mammalian (10), Rat (Rattus) (9), Mouse (Murine) (6), Chicken (4), Cat (Feline) (3), Dog (Canine) (1), Rabbit (1)
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Applications
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Western Blotting (WB) (28), Immunofluorescence (IF) (19), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Enzyme Immunoassay (EIA) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (IHC) (3), ELISA (2), ELISA (Detection) (2), Immunocytochemistry (ICC) (1)
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