Add to Basket
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) (AA 166-183) antibody

Antigen

Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3)
Synonyms
CC3, Lice, Yama, CPP32, Apopain, Caspase-3, A830040C14Rik, Cas3, Casp3, DECAY, Drosophila executioner caspase related to Apopain/Yama, caspase 3, DmelCG14902, CG14902, DRICE, ICE, DmelCG7788, CG7788,  ... show more
Epitope
Alternatives

AA 166-183
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Hamster
Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Catalog no. ABIN372208
Quantity 50 µg  (0.2 mg/ml)
Price 390.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies back to top

Characteristics Synonyms: CASP-3, CASP3, CPP32, CPP-32, Yama protein, Apopain, SCA-1, SCA1, Cysteine proteaseCPP32, SREBP cleavage activity 1
Alternative name Caspase-3
Swiss-Prot P42574
Immunogen Synthetic peptide corresponding to the amino acids 166-183 of Human Caspase-3. AA Sequence: TELDSGIETDSGVDDDMA
Cross-Reactivity Hamster, Human, Mouse (Murine), Baboon
Isotype IgG  (Matching secondary antibodies)
Description Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive(32kDa) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 andAsp175-Ser176 thereby generating two subunits of 17kDa and 12kDa, respectively. Recentstudies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to variety of apoptotic inducers including Fasmediated apoptosis.
Specificity This antibody is specific to Caspase 3 (CASP3). Species: Human. Predicted Species: Mouse, Baboon and Hamster. Others not tested.
Synonyms CC3, Lice, Yama, CPP32, Apopain, Caspase-3, A830040C14Rik, Cas3, Casp3, DECAY, Drosophila executioner caspase related to Apopain/Yama, caspase 3, DmelCG14902, CG14902, DRICE, ICE, DmelCG7788, CG7788, casp3, xcpp32, CASP3

Application Details
Alternatives Secondary Antibodies back to top

Application Notes Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.2 mg/ml
Purification Aff - Purified
Buffer TBS, pH 7.4 containing 0.02% Sodium Azide as preservative and 50%Glycerol BSA as stabilizer.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies back to top

Alternatives for antigen "Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3)", type "Antibodies"
Hosts Rabbit (75), Mouse (19), Goat (3)
Reactivities Human (89), Rat (Rattus) (42), Mouse (Murine) (41), Dog (Canine) (24), Cow (Bovine) (22), Pig (Porcine) (22), Rabbit (22), Sheep (Ovine) (21), Horse (Equine) (15), Hamster (7), Monkey (6), Chicken (4), Guinea Pig (3), Yeast (Pichia pastoris) (3)
Applications Western Blotting (WB) (67), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (26), Immunofluorescence (IF) (21), Flow Cytometry (FACS) (19), ELISA (13), Immunohistochemistry (IHC) (12), Immunoprecipitation (IP) (11), Enzyme Immunoassay (EIA) (6), Dot Blot (Dot) (2), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes active (18), Cleaved-Asp175 (3), active + pro (2), Ab-150 (1), Center (1), N-Term (1), p17 (1), p17 Cleaved-Asp175 (1), p32/p17 not p11 (1), pSer150 (1)