PAP Associated Domain Containing 7 (PAPD7) (AA 447-462) antibody

Catalog No. ABIN372376

Product Details

Target: PAP Associated Domain Containing 7 (PAPD7)

Binding Specificity: AA 447-462

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: GTASLKAVHH MSSPAI

Specificity: This antibody recognizes Polymerase (DNA Directed) Sigma (POLS/TRF4-1).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography.

Immunogen: Synthetic peptide containing amino acids 447-462 of human TRF4-1.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month (in aliquots) at-20 °C for longer.

Target Details

Target: PAP Associated Domain Containing 7 (PAPD7)

Alternative Name: PAPD7 / POLS / TRF4 (PAPD7 Products)

Synonyms: LAK-1 antibody, LAK1 antibody, POLK antibody, POLS antibody, TRF4 antibody, TRF4-1 antibody, TRF41 antibody, TUTASE5 antibody, TRF4-1b antibody, pols antibody, Pols antibody, DNA polymerase sigma antibody, poly(A) RNA polymerase D7, non-canonical antibody, non-canonical poly(A) RNA polymerase PAPD7 antibody, PAP associated domain containing 7 antibody, Eint_061490 antibody, PAPD7 antibody, LOC100579823 antibody, papd7 antibody, Papd7 antibody

Target Type: Viral Protein

Background: TRF4-1 is a nuclear protein whose expression is cell cycle-regulated at a post-transcriptional level. Two genes, TRF41 and TRF4-2, belonging to this family have been identified. TRF4 is also required to maintain a different aspect of higher order chromosome structure, sister chromatid cohesion.Synonyms: DNA polymerase kappa, DNA polymerase sigma, LAK-1, PAP-associated domain-containing protein 7, TRF-4, TUTase5, Terminal uridylyltransferase 5, Topoisomerase-related function protein 4-1

Molecular Weight: 60 kDa.

Gene ID: 11044

NCBI Accession: NP_001165276

UniProt: Q5XG87