PRDM5 antibody (AA 100-200)

Catalog No. ABIN372377

Product Details anti-PRDM5 Antibody

Target: PRDM5 (PR Domain Containing 5 (PRDM5))

Binding Specificity: AA 100-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRDM5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes PR Domain Containing 5 (PRDM5).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of amino acids 100-200 of human PRDM5 protein.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month (in aliquots) at-20 °C for longer.

Target Details for PRDM5

Target: PRDM5 (PR Domain Containing 5 (PRDM5))

Alternative Name: PRDM5 / PFM2 (PRDM5 Products)

Synonyms: PRDM5 antibody, BCS2 antibody, PFM2 antibody, 4432417F03Rik antibody, 6530401I24Rik antibody, AI197291 antibody, E130112L17Rik antibody, PR/SET domain 5 antibody, PR domain containing 5 antibody, PRDM5 antibody, prdm5 antibody, Prdm5 antibody

Background: PRDM5 is a transcription factor of the PR-domain protein family, and contains a PR-domain at the -NH2 terminus followed by 16 zinc finger motifs. It has been found to have a role in cell differentiation and tumorigenesis. A recombinant adenovirus expressing PRDM5 caused G2/M arrest and apoptosis upon infection of tumor cells. PRMD5 has been found to be silenced in breast, ovarian and lung cancers. The inactivation of PRDM5 may play a role in carcinogenesis.Synonyms: PR domain zinc finger protein 5, PR domain-containing protein 5

Molecular Weight: 73 kDa.

Gene ID: 11107

NCBI Accession: NP_061169

UniProt: Q9NQX1