CA2 antibody (HRP)

Catalog No. ABIN372476

Product Details anti-CA2 Antibody (HRP)

Target: CA2 (Carbonic Anhydrase II (CA2))

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti Rabbit serum, as well as purified and partially purified Carbonic Anhydrase II (Human Erythrocytes).

Cross-Reactivity (Details): Species reactivity (expected):Rabbit.
Species reactivity (tested):Human.

Purification: Ion Exchange Chromatography.

Immunogen: Carbonic Anhydrase II (Human Erythrocytes).

Isotype: IgG

Application Details

Application Notes: ELISA: 1/1000-1/6000. Western blot. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2 containing 0.01 % Gentamicin Sulfate as preservative and 10 mg/mL BSA as stabilizer, before the addition of Glycerol to 40 %

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CA2

Target: CA2 (Carbonic Anhydrase II (CA2))

Alternative Name: Carbonic Anhydrase 2 (CA2 Products)

Synonyms: CG6906 antibody, CT21171 antibody, Dmel\\CG6906 antibody, CA-2 antibody, caII antibody, car2 antibody, ca ii antibody, ca-ii antibody, BETA CA2 antibody, BETA CARBONIC ANHYDRASE 2 antibody, CA18 antibody, CARBONIC ANHYDRASE 18 antibody, CARBONIC ANHYDRASE 2 antibody, T9L3.40 antibody, T9L3_40 antibody, carbonic anhydrase 2 antibody, LOC100135827 antibody, AI131712 antibody, CAII antibody, Ca2 antibody, Car-2 antibody, Ltw-5 antibody, Lvtw-5 antibody, CA-II antibody, CAC antibody, Car2 antibody, CAR3 antibody, Carbonic anhydrase 2 antibody, carbonic anhydrase 2 L homeolog antibody, carbonic anhydrase 2 antibody, carbonic anhydrase 1 antibody, carbonic anhydrase II antibody, carbonic anhydrase, alpha type, periplasmic antibody, CAH2 antibody, ca2.L antibody, ca2 antibody, CA2 antibody, HCAG_04637 antibody, LOC100135827 antibody, LOC100635510 antibody, Car2 antibody, Ca2 antibody, LOC100154873 antibody, LOC101113341 antibody

Background: Carbonic anhydrase II (CAII) is a single polypeptide chain of molecular weight 29 kDa. It is present in the cytosol of most tissues, but highest concentrations are found, like Carbonic Anhydrase I, in erythrocytes. The concentration in erythrocytes is about 20μM. It catalyses the hydration of CO2 and the hydrolysis of esters. Zn2+ ion cofactor is required for enzyme activity. Certain point mutations occur without apparent clinical effect, however, complete absence leads to mild mental retardation and cerebral calcification, osteoporosis and renal tubular acidosis.Synonyms: CA-II, CA2, CAC, Carbonate dehydratase II, Carbonic anhydrase C, Carbonic anhydrase II

Gene ID: 760

NCBI Accession: NP_000058

UniProt: P00918