ROBO2 antibody (Internal Region)

Catalog No. ABIN372554

Product Details anti-ROBO2 Antibody

Target: ROBO2 (Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This ROBO2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: c-NQSQRPRPTK KHK

Specificity: Recognizes Roundabout homolog 2 (ROBO2).

Cross-Reactivity (Details): Species reactivity (expected):Dog (Canine), Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide from an internal region of human ROBO2.

Isotype: IgG

Application Details

Application Notes: ELISA: 1/16000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ROBO2

Target: ROBO2 (Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2))

Alternative Name: ROBO2 (ROBO2 Products)

Synonyms: SAX3 antibody, ROBO2 antibody, CG14347 antibody, CG14348 antibody, CG5481 antibody, CG5574 antibody, CT17326 antibody, D-Robo2 antibody, D-robo2 antibody, Dmel\\CG5481 antibody, Robo 2 antibody, Robo-2 antibody, Robo2 antibody, anon-EST:Liang-1.75 antibody, clone 1.75 antibody, dRobo-2 antibody, fus4 antibody, robo-2 antibody, robo2 antibody, unp1881 antibody, 2600013A04Rik antibody, 9430089E08Rik antibody, BB097918 antibody, D230004I22Rik antibody, mKIAA1568 antibody, sax3 antibody, roundabout guidance receptor 2 antibody, roundabout 2 antibody, roundabout, axon guidance receptor, homolog 2 (Drosophila) antibody, roundabout guidance receptor 2 S homeolog antibody, ROBO2 antibody, Robo2 antibody, robo2 antibody, robo2.S antibody

Background: The Roundabout (Robo) receptors and their secreted ligands Slits mediate a repulsive guidance system that prevents inappropriate axons from crossing the CNS midline. Additionally, Slits and their Robo receptors can also promote axonal branching and cell migration. Robo2 is a receptor for Slit2 and Slit1, which are thought to guide axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development.Synonyms: KIAA1568, ROBO-2, Roundabout homolog 2

Gene ID: 6092

NCBI Accession: NP_002933

UniProt: Q9HCK4

Pathways: Regulation of Cell Size