CNPase (CNP) antibody
| Antigen |
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| Synonyms |
CNP1, Cnp1, Cnp-1, CNPase, CNPF, CNPI, CNPII, CNP, sb:cb662, wu:fd44a05, wu:fi35d08, si:ch73-158e11.4, DKFZp469F1421 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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| Catalog no. |
ABIN372601 |
| Quantity |
50 µl |
| Price |
290.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: CNP, CNP1, Oligodendrocyte Marker, 2', 3'-cyclic-nucleotide 3'-phosphodiesterase
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Alternative name
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CNPase
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Swiss-Prot
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P09543
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Immunogen
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Endogenous rabbit 2,3-Cyclic Nucleotide-3-Phospho-Diesterase
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Cross-Reactivity
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Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine)
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Isotype
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IgG (Matching secondary antibodies)
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Description
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2,3-cyclic nucleotide-3-phosphodiesterase (CNP) is a membrane bound, microtubuleassociated protein that is among the most abundant myelin proteins of the CNS. It isthought that CNP may serve as a regulator of tubulin polymerization and of microtubuledistribution (Bifulco et al. , 2002). It was recently found that CNP may also function as apossible linker protein anchoring microtubules to the plasma membrane via a 13 residueC-terminal CNP fragment (Bifulco et al. , 2002, Esposito et al. , 2008).
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Specificity
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Specific for the ~46k CNP protein in Western blots. Species Reactivity: Tested: Human, Rabbit, Sheep, Mouse an Rat.
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Application Notes
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Western Blot: 1/1000. Immunohistochemitry: 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Purification
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Serum
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Storage
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Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Neurology, Glia marker
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Restrictions
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For Research Use only
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Alternatives for antigen "CNPase (CNP)", type "Antibodies"
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Hosts
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Rabbit (12), Mouse (4), Chicken (1)
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Reactivities
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Human (16), Mouse (Murine) (8), Rat (Rattus) (8), Cat (Feline) (1), Cow (Bovine) (1), Dog (Canine) (1), Pig (Porcine) (1), Rabbit (1), Sheep (Ovine) (1)
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Applications
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Western Blotting (WB) (15), ELISA (Detection) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), ELISA (2), Enzyme Immunoassay (EIA) (2), Immunofluorescence (IF) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), ELISA (Capture) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
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Epitopes
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AA 68-84 (1)
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