DBH antibody (N-Term)

Catalog No. ABIN372612

Product Details anti-DBH Antibody

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Binding Specificity: N-Term

Reactivity: Human, Non-Human Primate

Host: Sheep

Clonality: Polyclonal

Conjugate: This DBH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Specific for the ~75k DBH protein in Western blots.

Cross-Reactivity (Details): Species reactivity (tested):Human and non-Human Primates.

Purification: Affinity Chromatography using a Sulfo-Link® column matrix to which the peptide immunogen was coupled.

Immunogen: Peptide from the N-terminal region of human dopamine Beta-hydroxylase (DBH), conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at-20 °C.

Target Details for DBH

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Alternative Name: Dopamine beta-Hydroxylase (DBH Products)

Synonyms: CG1543 antibody, DBH antibody, Dbh antibody, Dmel\\CG1543 antibody, T beta h antibody, TBH antibody, TBetaH antibody, TBetah antibody, TBh antibody, TbetaH antibody, TbetaM antibody, Tbetah antibody, tbh antibody, DBM antibody, DOPBHY antibody, Tbh antibody, dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody, Tyramine beta hydroxylase antibody, MOXD1 homolog 2 antibody, dopamine beta hydroxylase antibody, dopamine beta-hydroxylase antibody, dbh antibody, Tbh antibody, LOC5574699 antibody, CpipJ_CPIJ004736 antibody, CpipJ_CPIJ004737 antibody, CpipJ_CPIJ014202 antibody, CpipJ_CPIJ016745 antibody, CpipJ_CPIJ019034 antibody, DBH antibody, Dbh antibody, LOC101110668 antibody

Background: DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001).Synonyms: DBH, DBM, DOPO, Dopamine beta-monooxygenase

Gene ID: 1621

NCBI Accession: NP_000778

UniProt: P09172

Pathways: Carbohydrate Homeostasis