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DLG4 antibody (N-Term)
DLG4
Reactivity: Rat, Mouse, Human, Cow, Zebrafish (Danio rerio), Non-Human Primate
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DLG4 Antibody
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Target
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DLG4
(Discs, Large Homolog 4 (Drosophila) (DLG4))
Binding Specificity
All epitopes for DLG4 antibodies
N-Term
Reactivity
All reactivities for DLG4 antibodies
Rat, Mouse, Human, Cow, Zebrafish (Danio rerio), Non-Human Primate
Host
All hosts for DLG4 antibodies
Rabbit
Clonality
All clonalities for DLG4 antibodies
Polyclonal
Conjugate
All conjugates for DLG4 antibodies
This DLG4 antibody is un-conjugated
Application
All applications for DLG4 antibodies
Western Blotting (WB)
Specificity
This antibody recognizes the ~95k PSD95 protein.
Cross-Reactivity (Details)
Species reactivity (expected):Human, Bovine, Zebrafish and non-Human Primates. Species reactivity (tested):Rat and Mouse.
Purification
Affinity Chromatography.
Immunogen
Peptide corresponding to amino acid residues from the N-terminal region of Rat PSD-95, conjugated to keyhole limpet hemocyanin (KLH).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Western blot: 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody undiluted (in aliquots) at-20 °C.
Target Details for DLG4
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Target
DLG4
(Discs, Large Homolog 4 (Drosophila) (DLG4))
Alternative Name
DLG4 / PSD95 (DLG4 Products )
Synonyms
11 antibody, CG1725 antibody, CG1730 antibody, CPD antibody, DLG antibody, DLG-A antibody, Discs-large antibody, Dlg antibody, Dlg-A antibody, Dlg1 antibody, DlgA antibody, Dmel\\CG1725 antibody, Drodlg antibody, PSD95 antibody, SAP97 antibody, anon-EST:Posey93 antibody, anon-WO03040301.258 antibody, anon-WO03040301.260 antibody, anon-WO03040301.268 antibody, d. lg.-1 antibody, dlg antibody, dlg-1 antibody, dlg-A antibody, dlgA antibody, dlgS97 antibody, l(1)10Bf antibody, l(1)G0276 antibody, l(1)G0342 antibody, l(1)G0456 antibody, l(1)G19 antibody, l(1)L11 antibody, l(1)bwn antibody, l(1)d.lg-1 antibody, l(1)d.lg.-1 antibody, l(1)discs large antibody, l(1)dlg antibody, l(1)dlg-1 antibody, l(1)dlg1 antibody, l(1)l.pr.-2 antibody, l(1)lpr-2 antibody, misb antibody, dlgh4 antibody, psd95 antibody, sap90 antibody, sap-90 antibody, LLGL1 antibody, Dlgh4 antibody, PSD-95 antibody, SAP90 antibody, SAP90A antibody, Sap90 antibody, SAP-90 antibody, DLG4 antibody, discs large 1 antibody, discs, large homolog 4 antibody, discs large MAGUK scaffold protein 4 antibody, discs, large homolog 4b (Drosophila) antibody, discs, large homolog 4 (Drosophila) antibody, dlg1 antibody, dlg4 antibody, DLG4 antibody, dlg4b antibody, Dlg4 antibody
Background
PSD95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004).Synonyms: DLGH4, Disks large homolog 4, PSD-95, Postsynaptic density protein 95, SAP-90, SAP90, Synapse-associated protein 90
Gene ID
29495
NCBI Accession
NP_062567
UniProt
P31016
Pathways
Regulation of Muscle Cell Differentiation , Synaptic Membrane , Skeletal Muscle Fiber Development , Asymmetric Protein Localization , Regulation of long-term Neuronal Synaptic Plasticity
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