RAB3A antibody (N-Term)

Catalog No. ABIN372708

Product Details anti-RAB3A Antibody

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Xenopus laevis, Non-Human Primate

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB3A antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody recognizes the ~27k Rab3 protein.

Cross-Reactivity (Details): Species reactivity (expected):Human, Mouse, Xenopus and non-Human Primates.
Species reactivity (tested):Rat.

Purification: Affinity Chromatography.

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of Rat Rab3, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at-20 °C.

Target Details for RAB3A

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Alternative Name: RAB3A (RAB3A Products)

Synonyms: RAB3 antibody, rab3a antibody, zgc:92276 antibody, RAB3A antibody, rab-3a antibody, si:ch211-255d18.4 antibody, zgc:112516 antibody, RAB3A, member RAS oncogene family antibody, RAB3A, member RAS oncogene family, a antibody, RAB3A, member RAS oncogene family L homeolog antibody, RAB3A, member RAS oncogene family, b antibody, RAB3A antibody, Rab3a antibody, rab3aa antibody, rab3a.L antibody, rab3a antibody, rab3ab antibody

Background: Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al., 2004). These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (Coppola et al., 2002). Specifically, Rab3's are thought to play a key role in presynaptic vesicle trafficking and priming (Schluter et al., 2006).Synonyms: RAB3A, RAB3B, RAB3C, RAB3D, Rab-3A, Rab-3B, Rab-3C, Rab-3D, Ras-related protein Rab-3A, Ras-related protein Rab-3B, Ras-related protein Rab-3C, Ras-related protein Rab-3D

Gene ID: 25531

NCBI Accession: NP_037150

UniProt: P63012

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport