Rab3 (N-Term) antibody

Antigen: Rab3

Epitope: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN372708

Additional Information

Characteristics: Synonyms: RAB3A, Rab-3A, RAB3B, Rab-3B, RAB3C, Rab-3C, RAB3D, Rab-3D, Ras-related proteinRab-3A, Ras-related protein Rab-3B, Ras-related protein Rab-3C, Ras-related proteinRab-3D

Gene ID: 25531

Swiss-Prot: P63012

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of Rat Rab3,conjugated to keyhole limpet hemocyanin (KLH).

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus), Xenopus laevis

Isotype: IgG  (Matching secondary antibodies)

Description: Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamilyhas 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al. , 2004). These proteins areexpressed in highest concentrations in brain and endocrine tissues and involved inregulated exocytosis of hormones and neurotransmitters (Coppola et al. , 2002). Specifically, Rab3’s are thought to play a key role in presynaptic vesicle trafficking andpriming (Schluter et al. , 2006).

Specificity: This antibody recognizes the ~27k Rab3 protein. Species Reactivity: Tested: Rat. Expected from sequence similarity: Human, Mouse, Xenopus and non-Human Primates.

Application Details

Application Notes: Western blot: 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Purification: Aff - Purified

Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% Glycerol.

Storage: Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Restrictions: For Research Use only