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SYT1 antibody

SYT1 Reactivity: Human, Rat, Mouse, Cow, Chicken, Non-Human Primate WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN372723
  • Target See all SYT1 Antibodies
    SYT1 (Synaptotagmin I (SYT1))
    Reactivity
    • 84
    • 70
    • 52
    • 12
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow, Chicken, Non-Human Primate
    Host
    • 96
    • 12
    • 4
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 103
    • 12
    Polyclonal
    Conjugate
    • 65
    • 9
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYT1 antibody is un-conjugated
    Application
    • 71
    • 42
    • 39
    • 17
    • 14
    • 13
    • 13
    • 11
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Specificity
    This antibody recognizes the ~65k Synaptotagmin I protein.
    Cross-Reactivity (Details)
    Species reactivity (expected):Human, Mouse, Bovine, Chicken and non-Human Primates.
    Species reactivity (tested):Rat.
    Purification
    Affinity Chromatography.
    Immunogen
    Synthetic peptide corresponding to amino acid residues within the Synaptotagmin-1 protein.
    Isotype
    IgG
    Top Product
    Discover our top product SYT1 Primary Antibody
  • Application Notes
    Western blot: 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody undiluted (in aliquots) at-20 °C.
  • Target
    SYT1 (Synaptotagmin I (SYT1))
    Alternative Name
    Synaptotagmin-1 (SYT1 Products)
    Synonyms
    P65 antibody, SVP65 antibody, SYT antibody, CG3139 antibody, D. Syt I antibody, DSYT antibody, DSYT2 antibody, DSypt antibody, DSyt antibody, Dmel\\CG3139 antibody, Droso1 antibody, Dsyt2 antibody, SYT I antibody, SYT1 antibody, Syt antibody, Syt 1 antibody, Syt I antibody, Syt-1 antibody, SytI antibody, dSYT antibody, dsyt1 antibody, dsytI antibody, l(2)23AB1 antibody, l(2)23Ba antibody, l(2)k05909 antibody, syt antibody, syt 1 antibody, syt I antibody, syt-1 antibody, syt1 antibody, sytI antibody, AW124717 antibody, G630098F17Rik antibody, Syti antibody, GB20036 antibody, DKFZP459P193 antibody, svp65 antibody, p65 antibody, wu:fj41c01 antibody, wu:fk56d05 antibody, zgc:92899 antibody, synaptotagmin 1 antibody, Synaptotagmin 1 antibody, synaptotagmin I antibody, synaptotagmin-1 antibody, synaptotagmin, p65 antibody, synaptotagmin Ia antibody, synaptotagmin 1 L homeolog antibody, SYT1 antibody, Syt1 antibody, Tsp_06980 antibody, Tsp_08220 antibody, syt1 antibody, LOC100533340 antibody, syt1a antibody, syt1.L antibody
    Background
    Synaptotagmin-1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release (Littleton and Bellen 1995). Recent studies indicate that Synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion (Zhang et al., 2002). It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size (Poskanzer et al., 2006).Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
    Gene ID
    6857
    NCBI Accession
    NP_001129277
    UniProt
    P21579
    Pathways
    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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