CES1 antibody (Internal Region)

Catalog No. ABIN372769

Product Details anti-CES1 Antibody

Target: CES1 (Carboxylesterase 1 (CES1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CES1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes Carboxylesterase 1 (CES1).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide (C-NTQAAQKLKDKE) from an internal region of Human CES1

Isotype: IgG

Application Details

Application Notes: ELISA: 1/8000. Western Blot: 0.03-0.1 μg/mL. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Alternative Name: CES1 / ACAT (CES1 Products)

Synonyms: ACAT antibody, CE-1 antibody, CEH antibody, CES2 antibody, HMSE antibody, HMSE1 antibody, PCE-1 antibody, REH antibody, SES1 antibody, TGH antibody, hCE-1 antibody, CESDD1 antibody, CES1 antibody, CES-K1 antibody, APLE antibody, PMPMEase antibody, CES antibody, carboxylesterase 1 antibody, liver carboxylesterase 1 antibody, liver carboxylesterase antibody, carboxylesterase 1 (monocyte/macrophage serine esterase 1) antibody, CES1 antibody, CpipJ_CPIJ013026 antibody, CpipJ_CPIJ016339 antibody, LOC100009551 antibody, LOC454097 antibody, LOC699486 antibody, LOC100050915 antibody

Background: The enzymes of the carboxylesterase family are widely distributed and can be found in the tissues of all animals. They differ in biochemical, immunological and genetic properties and play different roles depending on which part of the organism they are expressed in. In general, these carboxylesterases are responsible for detoxification, since they are able to degrade a number of exogenous compounds such as esters, amides and thioesters. Esterases cause esters to split into an acid and an alcohol within the human body, especially the ones found in nucleic acids (phosphodiester bonds) and lipids. Some types of esterase are found in lysozomes and are called acid hydrolase. Other types of esterase include: - Cholesterol esterase - Also referred to as cholesterol ester hydrolase and sterol esterase, cholesterol esterase is a form of esterase that occurs in the pancreas, the intestinal mucosa, the liver, and the kidney. It even occurs in the muscle. - Leukocyte esterase - Leukocyte esterase is used to determine whether or not white blood cells and irregularities that could cause infections are in the body. - Cholinesterase - Cholinesterase consists of acetylcholinesterase, which is found in the blood, and pseudocholinesterase, which is found in the blood plasma of the liver.Synonyms: Acyl coenzyme A:cholesterol acyltransferase, Brain carboxylesterase hBr1, CES2, Egasyn, HMSE, Liver carboxylesterase 1, Monocyte/macrophage serine esterase, Retinyl ester hydrolase, SES1, Serine esterase 1, Triacylglycerol hydrolase, hBr1

Gene ID: 1066

NCBI Accession: NP_001020365

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process