BCL7A antibody (C-Term)

Catalog No. ABIN374064

Product Details anti-BCL7A Antibody

Target: BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This BCL7A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: C-MKLEASQQNS EEM

Specificity: This antibody detects Bcl-7A at C-term.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein Genename: BCL7A

Application Details

Application Notes: Western Blot: 0.5-2 μg/mL. Approx 35 kDa band seen in HeLa cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for BCL7A

Target: BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))

Alternative Name: Bcl-7A (BCL7A Products)

Synonyms: BCL7 antibody, cb585 antibody, id:ibd1097 antibody, sb:cb585 antibody, wu:fk02d01 antibody, zgc:92023 antibody, 4432415N06Rik antibody, AI448316 antibody, bcl7a antibody, MGC89576 antibody, BCL7A antibody, BCL tumor suppressor 7A antibody, B-cell CLL/lymphoma 7A antibody, B cell CLL/lymphoma 7A antibody, B-cell CLL/lymphoma 7A L homeolog antibody, BCL7A antibody, bcl7a antibody, Bcl7a antibody, bcl7a.L antibody

Background: This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C.Synonyms: B-cell CLL/lymphoma 7 protein family member A, BCL7A

Gene ID: 605

NCBI Accession: NP_066273

UniProt: Q4VC05