Verified
GRB7
Reactivity: Human
WB, ELISA
Host: Goat
Polyclonal
unconjugated
Application Notes
Peptide ELISA: 1/32000. Western blot: 1 - 3 μg/mL. Approx 60-65 kDa band seen in A431 lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
GRB7
(Growth Factor Receptor-Bound Protein 7 (GRB7))
The Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediated by the SH2 domain. The protein also binds to ERBB2 and interacts with RND1.Synonyms: B47, Epidermal growth factor receptor GRB-7, GRB-7, GRB7 adapter protein, Growth factor receptor-bound protein 7