CBR1 antibody (C-Term)

Catalog No. ABIN374238

Product Details anti-CBR1 Antibody

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CBR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: C-HGQFVSEKRV EQW

Specificity: This antibody detects Human Carbonyl reductase 1 at C-term.

Purification: Ammonium Sulphate precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Syntehtic peptide from C-Terminus of Human Carbonyl reductase 1 (NP_001748.1) Genename: CBR1

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 16000. Western blot: 0.2-0.5 μg/mL. Approx 30-35 kDa band seen in Human Liver and Kidneylysates [Calculated MW of 30.5 kDa according to NP_001748.1]. Immunohistochemistry: 1-2 μg/mL. In paraffin embedded Human Kidney showscytoplasmic staining of epithelial cells of renal tubules.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Alternative Name: Carbonyl Reductase 1 (CBR1 Products)

Synonyms: LOC100222525 antibody, MGC131152 antibody, CBR antibody, SDR21C1 antibody, hCBR1 antibody, 9-KPR antibody, AW261796 antibody, CR antibody, Cbr antibody, carbonyl reductase 1 antibody, carbonyl reductase [NADPH] 1 antibody, carbonyl reductase 1 S homeolog antibody, carbonyl reductase antibody, cbr1 antibody, CBR1 antibody, LOC100222525 antibody, cbr1.S antibody, Smp_033530.3 antibody, LOC610164 antibody, Cbr1 antibody

Background: Carbonyl reductase is one of several monomeric, NADPH dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q.Synonyms: 15-hydroxyprostaglandin dehydrogenase [NADP+], CBR, CBR1, CRN, NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, Prostaglandin-E(2) 9-reductase

Molecular Weight: 30.4 kDa (NP_001748.1)

Gene ID: 873

NCBI Accession: NP_001748

UniProt: P16152