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PPP1R8 antibody (C-Term)

PPP1R8 Reactivity: Human, Mouse, Rat, Cow, Dog WB, IHC (p), EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374344
  • Target See all PPP1R8 Antibodies
    PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
    Binding Specificity
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 41
    • 33
    • 17
    • 17
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Human, Mouse, Rat, Cow, Dog
    Host
    • 40
    • 6
    • 2
    • 2
    Goat
    Clonality
    • 44
    • 6
    Polyclonal
    Conjugate
    • 29
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPP1R8 antibody is un-conjugated
    Application
    • 42
    • 15
    • 13
    • 13
    • 10
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Sequence
    C-EAWPGKKPTP SLLI
    Specificity
    This antibody detects NIPP-1 at C-term. It is expected to recognise all three Human isoforms of this protein.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Dog, Cow.
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
    Immunogen
    Peptide from C Terminus of the protein sequence according to NP_002704.1, NP_054829.2, NP_612568.1. Genename: PPP1R8
    Top Product
    Discover our top product PPP1R8 Primary Antibody
  • Application Notes
    Peptide ELISA: Limit dilution 1: 32000. Western blot: 1-2 μg/mL. Approx 40 kDa band observed in Human Lung and H460 cellextracts (predicted MW of 40 kDa according to NP_054829).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
    Alternative Name
    NIPP-1 (PPP1R8 Products)
    Synonyms
    ARD-1 antibody, ARD1 antibody, NIPP-1 antibody, NIPP1 antibody, PRO2047 antibody, 6330548N22Rik antibody, AU044684 antibody, PPP1R8 antibody, ard-1 antibody, ard1 antibody, nipp-1 antibody, nipp1 antibody, ppp1r8 antibody, si:ch211-206a7.1 antibody, protein phosphatase 1 regulatory subunit 8 antibody, protein phosphatase 1, regulatory subunit 8 antibody, protein phosphatase 1, regulatory (inhibitor) subunit 8 antibody, protein phosphatase 1, regulatory subunit 8b antibody, protein phosphatase 1 regulatory subunit 8 L homeolog antibody, protein phosphatase 1, regulatory subunit 8a antibody, protein phosphatase 1 regulatory subunit 8 S homeolog antibody, PPP1R8 antibody, Ppp1r8 antibody, ppp1r8b antibody, ppp1r8.L antibody, ppp1r8a antibody, ppp1r8.S antibody
    Background
    Inhibitor subunit of the major nuclear protein phosphatase 1 (PP1). It has RNA binding activity but does not cleave RNA and may target PP1 to RNA associated substrates. May also be involved in pre mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.Synonyms: ARD1, NIPP1, Nuclear inhibitor of protein phosphatase 1, PPP1R8
    Gene ID
    5511
    NCBI Accession
    NP_002704
    UniProt
    Q12972
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