OSBPL2 antibody (C-Term)

Catalog No. ABIN374376

Product Details anti-OSBPL2 Antibody

Target: OSBPL2 (Oxysterol Binding Protein-Like 2 (OSBPL2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This OSBPL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YFERNFSDCP DIY

Specificity: This antibody detects OSBPL2 at C-term. It is expected to recognise both reported isoforms.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, RatSpecies reactivity (tested):Human

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_055650.1, NP_653081.1. Genename: OSBPL2

Application Details

Application Notes: Peptide ELISA: Detection limit dilution 1: 16000. Western blot: 1-2 μg/mL. Approx 55-60 kDa band observed in Human Heart lysates(predicted MWs of 54 and 50 kDa according to NP_055650.1 and NP_653081.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for OSBPL2

Target: OSBPL2 (Oxysterol Binding Protein-Like 2 (OSBPL2))

Alternative Name: OSBPL2 (OSBPL2 Products)

Synonyms: Osbpl1a antibody, osbpl2 antibody, wu:fi36a04 antibody, zgc:55948 antibody, MGC52852 antibody, MGC130835 antibody, orp2 antibody, orp-2 antibody, MGC75824 antibody, OSBPL2 antibody, ORP-2 antibody, ORP2 antibody, C130070J12Rik antibody, Orp2 antibody, mKIAA0772 antibody, oxysterol binding protein-like 2b antibody, oxysterol binding protein like 2 L homeolog antibody, oxysterol binding protein like 2 antibody, oxysterol binding protein-like 2 antibody, osbpl2b antibody, osbpl2.L antibody, osbpl2 antibody, OSBPL2 antibody, Osbpl2 antibody

Background: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.Synonyms: KIAA0772, ORP-2, ORP2, OSBP-related protein 2, Oxysterol-binding protein-related protein 2

Gene ID: 9885

NCBI Accession: NP_055650

UniProt: Q9H1P3