RGS14 antibody (C-Term)

Catalog No. ABIN374433

Product Details anti-RGS14 Antibody

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This RGS14 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: C-IGGSLNSTTD SAL

Specificity: This antibody recognizes RGS14.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the C Terminus of the protein sequence according to NP_006471.

Application Details

Application Notes: Peptide ELISA: 1/16,000. Western Blot: 0.5-2 μg/mL. Blot: Approx 65-70 kDa band observed in Jurkat lysates(predicted MW of 60 kDa according to NP_006471).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RGS14

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Alternative Name: RGS14 (RGS14 Products)

Synonyms: RPIP1 antibody, MGC80558 antibody, RGS14 antibody, rgs14 antibody, wu:fi04g12 antibody, regulator of G protein signaling 14 antibody, regulator of G-protein signaling 14 antibody, regulator of G-protein signaling 14 L homeolog antibody, regulator of G-protein signalling 14 antibody, regulator of G protein signaling 14a antibody, RGS14 antibody, Rgs14 antibody, rgs14.L antibody, rgs14 antibody, rgs14a antibody

Background: RGS14 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP bound form. Contains 1 GoLoco domain, 2 Ras binding (RBD) domains, 1 RGS domain.Synonyms: Regulator of G-protein signaling 14

Gene ID: 10636

NCBI Accession: NP_006471

UniProt: O43566

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling