CD2BP2 antibody (N-Term)

Catalog No. ABIN374445

Product Details anti-CD2BP2 Antibody

Target: CD2BP2 (CD2 (Cytoplasmic Tail) Binding Protein 2 (CD2BP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This CD2BP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: C-PKRKVTFQGV GDE

Specificity: This antibody recognizes CD2BP2.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the N Terminus of the protein sequence according to NP_006101.1.

Application Details

Application Notes: Peptide ELISA: 1/32,000. Western Blot: 0.3-1.0 μg/mL. Detects a band of Approx 50 kDa in Human Lymph Node,Thymus and Tonsil lysates (Predicted Molecular Weight: 37.0 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for CD2BP2

Target: CD2BP2 (CD2 (Cytoplasmic Tail) Binding Protein 2 (CD2BP2))

Alternative Name: CD2BP2 (CD2BP2 Products)

Synonyms: FWP010 antibody, LIN1 antibody, PPP1R59 antibody, Snu40 antibody, U5-52K antibody, 1500011B02Rik antibody, 2410024K20Rik antibody, AW048183 antibody, CD2 cytoplasmic tail binding protein 2 antibody, Cd2 (cytoplasmic tail) binding protein 2 antibody, CD2 antigen (cytoplasmic tail) binding protein 2 antibody, CD2BP2 antibody, Cd2bp2 antibody

Background: CD2BP2 is an intracellular protein which binds to a site containing two PPPGHR segments within the cytoplasmic region of CD2. Mutagenesis and NMR analysis demonstrated that the CD2 binding region of CD2BP2 includes a 17 amino acid motif also found in several yeast and Caenorhabditis elegans proteins of unknown function. In Jurkat T cells, over expression of the isolated CD2BP2 domain binding to CD2 enhances the production of interleukin 2 on crosslinking of CD2 but not the T cell receptor.Synonyms: CD2 antigen cytoplasmic tail-binding protein 2, CD2 cytoplasmic domain-binding protein, CD2 tail-binding protein, KIAA1178

Gene ID: 10421, 9606

UniProt: O95400

Pathways: Ribonucleoprotein Complex Subunit Organization