ZDHHC17 antibody (C-Term)

Catalog No. ABIN374510

Product Details anti-ZDHHC17 Antibody

Target: ZDHHC17 (Zinc Finger, DHHC-Type Containing 17 (ZDHHC17))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Chimpanzee

Host: Goat

Clonality: Polyclonal

Conjugate: This ZDHHC17 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody recognizes HIP14/ZDHHC17.

Cross-Reactivity (Details): Species reactivity (expected):Rat, Canine (Dog) and Bovine.
Species reactivity (tested):Human, Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence CYDQISGSGYQLV, from the C Terminus of the protein sequence according to NP_056151.2. Genename: ZDHHC17

Application Details

Application Notes: Peptide ELISA: Detection Limit Dilution: 1/8000. Western blot: 1-3 μg/mL. Approx 70 kDa band observed in Human and Mouse Brain lysates(Calculated MW of 72.0 kDa according to NP_056151.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ZDHHC17

Target: ZDHHC17 (Zinc Finger, DHHC-Type Containing 17 (ZDHHC17))

Alternative Name: HIP14 / ZDHHC17 (ZDHHC17 Products)

Synonyms: A230053P19Rik antibody, BB187739 antibody, D130071N24Rik antibody, Hip14 antibody, HIP14 antibody, HIP3 antibody, HYPH antibody, si:ch211-81a6.1 antibody, zinc finger DHHC-type containing 17 antibody, zinc finger, DHHC domain containing 17 antibody, zinc finger, DHHC-type containing 17 antibody, ZDHHC17 antibody, zdhhc17 antibody, Zdhhc17 antibody

Background: ZDHHC17 (HIP14) is a neuronal palmitoyl transferase. Palmitoylation is critical for trafficking and function of signaling molecules, neurotransmitter receptors, and synaptic scaffolding proteins in neurons. ZDHHC17 causes cellular transformation. It has been shown that mRNA encoding ZDHHC17 is up-regulated in a number of types of human tumors, thus ZDHHC17 and other PATs (palmitoyl acyltransferases) are potential targets for new anticancer drugs.Synonyms: DHHC-17, HIP3, HSPC294, HYPH, Huntingtin-interacting protein 14, Huntingtin-interacting protein 3, Huntingtin-interacting protein H, KIAA0946, Palmitoyltransferase ZDHHC17, Zinc finger DHHC domain-containing protein 17

Gene ID: 23390

NCBI Accession: NP_056151

UniProt: Q8IUH5