TFAP2C antibody (C-Term)

Catalog No. ABIN374524

Product Details anti-TFAP2C Antibody

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This TFAP2C antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: C-NKTLEKMEKH RK

Specificity: This antibody recognizes Transcription factor AP2 gamma.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the C Terminus of the protein sequence Genename: TFAP2C

Application Details

Application Notes: Peptide ELISA: 1/128000. Western Blot. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TFAP2C

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Alternative Name: AP2-gamma / TFAP2C (TFAP2C Products)

Synonyms: erf1 antibody, hap-2g antibody, tfa2pc antibody, tfap2g antibody, ap2-gamma antibody, TFAP2C antibody, AP2-gamma antibody, Tcfap2c antibody, AP2-GAMMA antibody, ERF1 antibody, TFAP2G antibody, hAP-2g antibody, wu:fb48g05 antibody, wu:fb49c04 antibody, zgc:92088 antibody, ap-2g antibody, tfap2gamma antibody, AA409384 antibody, AP2gamma antibody, Ap-2.2 antibody, Stra2 antibody, transcription factor AP-2 gamma antibody, putative transcription factor ap-2 gamma antibody, transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) antibody, transcription factor AP-2 gamma S homeolog antibody, transcription factor AP-2, gamma antibody, tfap2c antibody, TFAP2C antibody, Smp_157840 antibody, Tfap2c antibody, tfap2c.S antibody

Background: AP2 gamma is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.Synonyms: Activating enhancer-binding protein 2 gamma, ERF-1, ERF1, Transcription factor AP2 gamma, Transcription factor ERF-1

Gene ID: 7022, 9606

UniProt: Q92754

Pathways: Stem Cell Maintenance