PCSK9 antibody (C-Term)

Catalog No. ABIN374535

Product Details anti-PCSK9 Antibody

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This PCSK9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: CRSRHLAQAS QELQ

Specificity: This antibody recognizes Human PCSK9 at C-term. Other Species not tested.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Synthetic peptide from the C-Terminus of Human PCSK9 (NP_777596.2) Genename: PCSK9

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 0.3 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PCSK9

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Alternative Name: PCSK9 (PCSK9 Products)

Synonyms: FH3 antibody, HCHOLA3 antibody, LDLCQ1 antibody, NARC-1 antibody, NARC1 antibody, PC9 antibody, AI415265 antibody, AI747682 antibody, Narc1 antibody, proprotein convertase subtilisin/kexin type 9 antibody, proprotein convertase subtilisin/kexin type 9 L homeolog antibody, PCSK9 antibody, pcsk9.L antibody, pcsk9 antibody, Pcsk9 antibody

Background: PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. PCSK9 may function as a proprotein convertase. PCSK9 plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in PCSK9 gene have been associated with a third form of autosomal dominant familial hypercholesterolemia.Synonyms: NARC-1, NARC1, Neural apoptosis-regulated convertase 1, PCSK-9, Proprotein convertase PC9, Proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9

Gene ID: 255738

NCBI Accession: NP_777596

UniProt: Q8NBP7