CHMP5 antibody (C-Term)

Catalog No. ABIN374544

Product Details anti-CHMP5 Antibody

Target: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This CHMP5 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to CHMP5.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-NKDGVLVDEFGLPQ, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/8000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CHMP5

Target: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Alternative Name: CHMP5 (CHMP5 Products)

Synonyms: SNF7DC2 antibody, cgi-34 antibody, hspc177 antibody, pnas-2 antibody, vps60 antibody, chmp5 antibody, zgc:64125 antibody, C9orf83 antibody, HSPC177 antibody, PNAS-2 antibody, Vps60 antibody, 2210412K09Rik antibody, AW545668 antibody, RGD1305968 antibody, charged multivesicular body protein 5 S homeolog antibody, charged multivesicular body protein 5b antibody, charged multivesicular body protein 5 antibody, charged multivesicular body protein 5 L homeolog antibody, chromatin modifying protein 5 antibody, chmp5.S antibody, chmp5b antibody, CHMP5 antibody, chmp5.L antibody, chmp5 antibody, Chmp5 antibody

Background: CHMP5 is a component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo.Synonyms: C9orf83, CHMP-5, Charged multivesicular body protein 5, Chromatin-modifying protein 5, SNF7 domain-containing protein 2, SNF7DC2, Vacuolar protein-sorting-associated protein 60, Vps60, hVps60

Gene ID: 51510

NCBI Accession: NP_057494

UniProt: Q9NZZ3