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ADAM33 antibody (ADAM Metallopeptidase Domain 33) (Internal Region)

Details for Product anti-ADAM33 Antibody No. ABIN374562, Supplier: Log in to see
Antigen
  • ADAM13
  • ADAM33
  • Adaml
  • adam13
  • C20orf153
  • DJ964F7.1
Epitope
Internal Region
12
2
2
2
1
1
1
1
Reactivity
Human
33
13
3
3
1
Host
Goat
29
14
3
Clonality
Polyclonal
Conjugate
This ADAM33 antibody is un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
30
20
11
6
2
2
1
1
Supplier
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Immunogen Peptide with sequence CQSRRCRKNAFQEL, from the internal region of the protein sequence
Specificity This antibody is expected to recognise isoform alpha of ADAM33 and not isoform beta.
Purification Affinity chromatography
Alternative Name ADAM33 (ADAM33 Antibody Abstract)
Background ADAM33, also known as A disintegrin and metalloproteinase 33, is a member of the metalloproteinase family containing disintegrin-like domains (ADAMs). ADAM33 appears to be widely expressed and found in most organs. ADAM33 may act as a cell-attachment molecule, by binding integrins through the cysteine-rich domain. Recent work suggests that mutations in ADAM33 may be linked to asthma and that many of the mutations generate new cysteine residues, which may disturb the function of ADAM33.Synonyms: Disintegrin and metalloproteinase domain-containing protein 33
Gene ID 80332, 9606
UniProt Q9BZ11
Research Area Proteolysis / Ubiquitin, Metalloprotease, Extracellular Matrix, Proteases
Application Notes Peptide ELISA: 1/64000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-ADAM33 antibody (ADAM Metallopeptidase Domain 33) (Internal Region) (ABIN374562) anti-ADAM Metallopeptidase Domain 33 (ADAM33) (Internal Region) antibody
Background publications Blakey, Halapi, Bjornsdottir et al.: "Contribution of ADAM33 polymorphisms to the population risk of asthma." in: Thorax, Vol. 60, Issue 4, pp. 274-6, 2005 (PubMed).