Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CBX5 antibody (Internal Region)

CBX5 Reactivity: Human, Mouse, Dog WB, IHC (p) Host: Goat Polyclonal unconjugated
Catalog No. ABIN374617
  • Target See all CBX5 Antibodies
    CBX5 (Chromobox Homolog 5 (CBX5))
    Binding Specificity
    • 15
    • 15
    • 12
    • 11
    • 10
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 114
    • 49
    • 28
    • 15
    • 8
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Human, Mouse, Dog
    Host
    • 120
    • 18
    • 2
    • 1
    Goat
    Clonality
    • 111
    • 29
    • 1
    Polyclonal
    Conjugate
    • 68
    • 10
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CBX5 antibody is un-conjugated
    Application
    • 91
    • 56
    • 28
    • 26
    • 26
    • 23
    • 17
    • 10
    • 10
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody recognizes Human Chromobox protein homolog 5 (CBX5).
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    Immunogen
    Peptide with sequence C-NKRKSNFSNSADDIK, from the internal region of the protein sequence according to NP_036249.1, NP_001120793.1, NP_001120794.1. .Remarks: Variants (NP_036249.1, NP_001120793.1, NP_001120794.1) encode the same protein
    Top Product
    Discover our top product CBX5 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/128000. Western Blot: 0.03 - 0.1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CBX5 (Chromobox Homolog 5 (CBX5))
    Alternative Name
    CBX5 (CBX5 Products)
    Synonyms
    HP1 antibody, HP1A antibody, id:ibd2026 antibody, wu:fc63e02 antibody, wu:fe47g12 antibody, wu:fi03h05 antibody, zgc:158601 antibody, CBX5 antibody, cbx5 antibody, MGC64354 antibody, 2610029O15Rik antibody, C75991 antibody, Hp1a antibody, Hp1alpha antibody, chromobox 5 antibody, chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody, chromobox 5 S homeolog antibody, CBX5 antibody, cbx5 antibody, Cbx5 antibody, cbx5.S antibody
    Background
    HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.Synonyms: Chromobox protein homolog 5, HP1 alpha, HP1-alpha, HP1A, Heterochromatin protein 1 homolog alpha, p25
    Molecular Weight
    22.2 kDa (NP_036249.1)
    Gene ID
    23468, 9606
    UniProt
    P45973
You are here:
Support