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FZD8 antibody (C-Term)

FZD8 Reactivity: Human, Mouse, Rat, Cow, Dog WB, IHC (p) Host: Goat Polyclonal unconjugated
Catalog No. ABIN374634
  • Target See all FZD8 Antibodies
    FZD8 (Frizzled Family Receptor 8 (FZD8))
    Binding Specificity
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 54
    • 43
    • 31
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog
    Host
    • 52
    • 3
    • 1
    • 1
    Goat
    Clonality
    • 48
    • 9
    Polyclonal
    Conjugate
    • 26
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FZD8 antibody is un-conjugated
    Application
    • 37
    • 15
    • 12
    • 11
    • 10
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody reacts to Frizzled-8.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Bovine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-SYPKQMPLSQV, from the C Terminus of the protein sequence
    Top Product
    Discover our top product FZD8 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL. Immunohistochemistry on paraffin sections: 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    FZD8 (Frizzled Family Receptor 8 (FZD8))
    Alternative Name
    FZD8 / Frizzled-8 (FZD8 Products)
    Synonyms
    FZ-8 antibody, hFZ8 antibody, FZD8 antibody, Fz-8 antibody, frizzled8 antibody, xfz8 antibody, Xfz8 antibody, frizzled-8 antibody, hfz8 antibody, Fz8 antibody, fzd8 antibody, fz5 antibody, fz8a antibody, fzc antibody, wu:fd02c05 antibody, zg05 antibody, ZG06 antibody, Zfz8b antibody, fz6 antibody, fz8b antibody, fzA antibody, ik:tdsubc_1e1 antibody, xx:tdsubc_1e1 antibody, zfzA antibody, frizzled class receptor 8 antibody, frizzled class receptor 8 S homeolog antibody, frizzled class receptor 8 L homeolog antibody, frizzled class receptor 8a antibody, frizzled class receptor 8b antibody, FZD8 antibody, fzd8.S antibody, fzd8 antibody, Fzd8 antibody, fzd8.L antibody, fzd8a antibody, fzd8b antibody
    Background
    Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.Synonyms: Fz-8, hFz8
    Gene ID
    8325
    NCBI Accession
    NP_114072
    UniProt
    Q9H461
    Pathways
    WNT Signaling
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