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PDE4D antibody (C-Term)

PDE4D Reactivity: Human, Mouse WB, EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374635
  • Target See all PDE4D Antibodies
    PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
    Binding Specificity
    • 16
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 51
    • 43
    • 41
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 53
    • 2
    • 1
    Goat
    Clonality
    • 54
    • 2
    Polyclonal
    Conjugate
    • 28
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDE4D antibody is un-conjugated
    Application
    • 43
    • 20
    • 18
    • 17
    • 11
    • 10
    • 10
    • 6
    • 5
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequence
    QPEACVIDDR SPDT
    Specificity
    This antibody detects PDE4D at C-term and is expected to recognize all reported isoforms.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    Immunogen
    Peptide with sequence from the C-Terminus of the protein sequence according to NP_001098101.1, NP_006194.2, NP_001159371.1. Genename: PDE4D
    Top Product
    Discover our top product PDE4D Primary Antibody
  • Application Notes
    Peptide ELISA: 1/128000. Western Blot. : 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
    Alternative Name
    PDE4D (PDE4D Products)
    Synonyms
    ACRDYS2 antibody, DPDE3 antibody, HSPDE4D antibody, PDE43 antibody, PDE4DN2 antibody, STRK1 antibody, CMYA2 antibody, MMGL antibody, 9630011N22Rik antibody, Dpde3 antibody, 4732458A06Rik antibody, 9430063L05Rik antibody, C87016 antibody, D130016K21Rik antibody, D3Bwg1078e antibody, Usmg4 antibody, mKIAA0454 antibody, si:dkey-190g11.2 antibody, phosphodiesterase 4D antibody, phosphodiesterase 4D interacting protein antibody, phosphodiesterase 4D, cAMP specific antibody, phosphodiesterase 4D, cAMP-specific antibody, phosphodiesterase 4D interacting protein (myomegalin) antibody, PDE4D antibody, PDE4DIP antibody, pde4d antibody, Pde4dip antibody, Pde4d antibody
    Background
    Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'- monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE4 enzyme belongs to a family of cAMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cAMP. Four genes (4A, 4B, 4C, and 4D) encode around 20 distinct isoform members of the PDE4 family. Each isoform is characterized by a unique N-terminal region.Synonyms: 5'-cyclic phosphodiesterase 4D, DPDE3, EC=3.1.4.17, PDE43, PDE4D, cAMP-specific 3'
    Gene ID
    5144
    NCBI Accession
    NP_001098101
    UniProt
    Q08499
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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