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DCP1A antibody (C-Term)

DCP1A Reactivity: Human, Mouse, Rat WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN374653
  • Target See all DCP1A Antibodies
    DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))
    Binding Specificity
    • 10
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 65
    • 19
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 57
    • 7
    • 1
    Goat
    Clonality
    • 52
    • 13
    Polyclonal
    Conjugate
    • 34
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    This DCP1A antibody is un-conjugated
    Application
    • 42
    • 26
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody reacts to DCP1A.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-QVLTKNKDNHN, from the C Terminus of the protein sequence
    Top Product
    Discover our top product DCP1A Primary Antibody
  • Application Notes
    Peptide ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))
    Alternative Name
    DCP1A (DCP1A Products)
    Synonyms
    DCP1A antibody, 1110066A22Rik antibody, 4930568L04Rik antibody, AU019772 antibody, D14Ertd817e antibody, Mitc1 antibody, SMIF antibody, RGD1561298 antibody, mitc1 antibody, HSA275986 antibody, Nbla00360 antibody, SMAD4IP1 antibody, smad4ip1 antibody, smif antibody, decapping mRNA 1A antibody, decapping mRNA 1A L homeolog antibody, DCP1A antibody, Dcp1a antibody, dcp1a antibody, dcp1a.L antibody
    Background
    Dcp1a is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. Dcp1a binds DCP1B, DCP2, RENT1 and SMAD4 and forms part of a cytoplasmic complex containing proteins involved in mRNA decay, including XRN1 and LSM1.Synonyms: SMIF, Smad4-interacting transcriptional co-activator, Transcription factor SMIF, mRNA-decapping enzyme 1A
    Gene ID
    55802, 9606
    UniProt
    Q9NPI6
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